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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
transient receptor potential cation channel subfamily C member 3
Summary
- Gene Symbol
-
- TRPC3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ANK repeat
- Alternative splicing
- Calcium channel
- Cell membrane
- Disease variant
- Glycoprotein
- Metal-binding
- Reference proteome
- Repeat
- Spinocerebellar ataxia
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q13507 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of cardiac muscle hypertrophy in response to stress | ||
| response to calcium ion | ||
| regulation of cytosolic calcium ion concentration | ||
| calcium ion transmembrane transport | ||
| phototransduction |
GO Hierarchy
biological process
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| cation channel complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| store-operated calcium channel activity | ||
| metal ion binding | ||
| calcium channel activity | ||
| calcium-activated cation channel activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- short transient receptor potential channel
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050742 | nicotine dependence | |
| DOID:0111744 | cerebellar ataxia type 41 | |
| DOID:6432 | pulmonary hypertension |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 22065 | MGI:109526 | MOUSE36894 | ||
| 60395 | RGD:61973 | RATNO25622 | ||
| 176202 | WB:WBGene00006614 | |||
| 286866 | BOVIN09230 | |||
| 397210 | PIGXX34179 | |||
| 471294 | 9598_0:001474 | PANTR34425 | ||
| 483844 | CANLF06287 | |||
| 707586 | MACMU36650 | |||
| 100016978 | MONDO25728 | |||
| 100072204 | HORSE28780 |
