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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
transient receptor potential cation channel subfamily C member 6
Summary
- Gene Symbol
-
- TRPC6
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ANK repeat
- Alternative splicing
- Calcium channel
- Cell membrane
- Disease variant
- Glycoprotein
- Phosphoprotein
- Reference proteome
- Repeat
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9Y210 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of cytosolic calcium ion concentration | ||
| monoatomic cation transport | ||
| calcium ion transmembrane transport | ||
| positive regulation of ion transmembrane transporter activity | ||
| single fertilization |
GO Hierarchy
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| store-operated calcium channel activity | ||
| calcium channel activity | ||
| protein homodimerization activity | ||
| inositol 1,4,5 trisphosphate binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- short transient receptor potential channel
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050742 | nicotine dependence | |
| DOID:0080379 | nephrotic syndrome type 2 | |
| DOID:0111129 | focal segmental glomerulosclerosis 2 | |
| DOID:1312 | focal segmental glomerulosclerosis | |
| DOID:224 | transient cerebral ischemia | |
| DOID:557 | kidney disease | |
| DOID:576 | proteinuria | |
| DOID:6432 | pulmonary hypertension | |
| DOID:8544 | chronic fatigue syndrome | |
| DOID:9352 | type 2 diabetes mellitus |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 22068 | MGI:109523 | MOUSE61641 | ||
| 89823 | RGD:619788 | |||
| 176202 | WB:WBGene00006614 | |||
| 407151 | BOVIN06357 | |||
| 451503 | 9598_0:003270 | PANTR04154 | ||
| 563989 | ZFIN:ZDB-GENE-040724-114 | DANRE20929 | ||
| 703611 | MACMU10176 | |||
| 100011660 | MONDO21792 | |||
| 100061175 | HORSE38136 | |||
| 100079408 | ORNAN13763 |
