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TUB bipartite transcription factor

Summary

Gene Symbol

Organism

Homo sapiens (human)

External Links

NCBI Gene

7275

PubChem

7275

Alliance of Genome Resources

HGNC:12406

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Cytoplasm
Nucleus
Obesity
Phagocytosis
Reference proteome
Secreted
Sensory transduction

Proteins

Displaying 1 entry
UniProt	Protein Name
P50607

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
sensory perception of sound	IEA
regulation of G protein-coupled receptor signaling pathway	IEA
intraciliary transport	IDA	28154160
retina development in camera-type eye	IEA
positive regulation of phagocytosis	IDA	19837063

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

transport along microtubule [inference]

intraciliary transport

cell recognition [inference]

phagocytosis, recognition

cellular localization [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

intraciliary transport

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to ciliary membrane [inference]

receptor localization to non-motile cilium

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium

protein localization to non-motile cilium [inference]

protein localization to ciliary membrane [inference]

receptor localization to non-motile cilium

protein localization to membrane [inference]

protein localization to ciliary membrane [inference]

receptor localization to non-motile cilium

protein localization to cell periphery [inference]

protein localization to ciliary membrane [inference]

receptor localization to non-motile cilium

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

photoreceptor cell maintenance

developmental process [inference]

anatomical structure development [inference]

retina development in camera-type eye

localization [inference]

protein-containing complex localization [inference]

intraciliary transport

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium

protein localization to non-motile cilium [inference]

protein localization to ciliary membrane [inference]

receptor localization to non-motile cilium

protein localization to membrane [inference]

protein localization to ciliary membrane [inference]

receptor localization to non-motile cilium

protein localization to cell periphery [inference]

protein localization to ciliary membrane [inference]

receptor localization to non-motile cilium

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

intraciliary transport

microtubule-based transport [inference]

transport along microtubule [inference]

intraciliary transport

establishment of localization in cell [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

intraciliary transport

cellular localization [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

intraciliary transport

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to ciliary membrane [inference]

receptor localization to non-motile cilium

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium

protein localization to non-motile cilium [inference]

protein localization to ciliary membrane [inference]

receptor localization to non-motile cilium

protein localization to membrane [inference]

protein localization to ciliary membrane [inference]

receptor localization to non-motile cilium

protein localization to cell periphery [inference]

protein localization to ciliary membrane [inference]

receptor localization to non-motile cilium

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway

regulation of localization [inference]

regulation of transport [inference]

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of phagocytosis [inference]

positive regulation of phagocytosis

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of phagocytosis [inference]

positive regulation of phagocytosis

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of phagocytosis [inference]

positive regulation of phagocytosis

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
plasma membrane	IEA
extracellular region	IEA
nucleus	IDA	28154160
cytosol	IEA
cytoplasm	IDA	28154160

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
intraciliary transport particle A binding	IDA	28154160
protein-containing complex binding	IDA	20889716
G protein-coupled receptor binding	IDA	28154160

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

G protein-coupled receptor binding

protein-containing complex binding

intraciliary transport particle A binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Tubby

Functional Category

C: Energy production and conversion
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Tubby, C-terminal
Tubby-like, C-terminal

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:9970	obesity	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 89 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	22141		MGI:2651573	MOUSE52920
Rattus norvegicus	25609		RGD:3918	RATNO21198
Drosophila melanogaster	37400		FB:FBgn0015721
Caenorhabditis elegans	174312		WB:WBGene00006655
Xenopus laevis	444597		Xenbase:XB-GENE-962286
Pan troglodytes	466436	9598_0:002f40		PANTR02249
Xenopus tropicalis	493219		Xenbase:XB-GENE-962281
Danio rerio	568677		ZFIN:ZDB-GENE-121009-1	DANRE41572
Macaca mulatta	706054			MACMU09904
Monodelphis domestica	100029301			MONDO26985