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alanine--glyoxylate aminotransferase

Summary

Gene Symbol

AGXT

Organism

Felis catus (domestic cat)

External Links

NCBI Gene: 727692
KEGG Gene ID: fca:727692
PubChem: 727692

Annotation

Keyword

Acetylation
Alternative initiation
Aminotransferase
Mitochondrion
Peroxisome
Pyridoxal phosphate
Reference proteome
Transit peptide

Proteins

Displaying 1 entry
UniProt	Protein Name
P41689	Serine--pyruvate aminotransferase, mitochondrial

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
glycine biosynthetic process, by transamination of glyoxylate	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

primary metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

Displaying 1 entry
GO Term	Evidence Code	PMID
peroxisome	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
serine-pyruvate transaminase activity	IEA	30032202
alanine-glyoxylate transaminase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring nitrogenous groups [inference]

transaminase activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00830

Name

alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]

References

Rhea

pyruvate + L-serine

3-hydroxypyruvate + L-alanine

Enzyme

2.6.1.51

PMID

glyoxylate + L-alanine

pyruvate + glycine

Enzyme

2.6.1.44

PMID

2-oxobutanoate + L-alanine

pyruvate + (2S)-2-aminobutanoate

Enzyme

2.6.1.44

PMID

2123486

Ortholog

Displaying entries **61 - 65** of 65 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Equus asinus asinus	106832216		EQUAS24576
Echeneis naucrates	115042318		ECHNA36204
Propithecus coquereli	105824830		PROCO31399
Nannospalax galili	103730838		NANGA13371
Carlito syrichta	103256358		CARSF09966

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024