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Standards Ontologies Notations
surfactant protein A2

Summary
Gene Symbol
  • SFTPA2
Aliases
  • COLEC5
  • SP-A2
  • surfactant, pulmonary-associated protein A2A
Organism
Homo sapiens (human)
External Links
NCBI Gene
729238
HGNC
10799
KEGG Gene ID
hsa:729238
PubChem
729238
Alliance of Genome Resources
Annotation
Keyword
  • Acetylation
  • Calcium
  • Collagen
  • Disease variant
  • Disulfide bond
  • Extracellular matrix
  • Glycoprotein
  • Hydroxylation
  • Lectin
  • Reference proteome
  • Signal
  • Surface film
Proteins
Displaying 1 entry
UniProt Protein Name
Q8IWL1
  • 35 kDa pulmonary surfactant-associated protein
  • Alveolar proteinosis protein
  • Collectin-5
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 7 in total
GO Term Evidence Code PMID
lamellar body
collagen trimer
extracellular region
endoplasmic reticulum membrane
multivesicular body
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
Human Protein Atlas
ENSG00000185303

soft tissue soft tissue blood blood blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node kidney kidney adrenal gland adrenal gland breast breast duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland nasopharynx nasopharynx tongue tonsil tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder ductus deferens ductus deferens seminal vesicle seminal vesicle seminal vesicle seminal vesicle testis testis epididymis epididymis brain smooth muscle urinary bladder prostate bone marrow skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus cartilage sole of foot sole of foot soft tissue blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lactating breast lactating breast kidney kidney adrenal gland adrenal gland duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland salivary gland salivary gland salivary gland salivary gland salivary gland nasopharynx tongue tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder brain skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus smooth muscle urinary bladder vagina ovary ovary fallopian tube fallopian tube endometrium placenta cervix cervix bone marrow cartilage sole of foot sole of foot olfactory region cerebral cortex cerebellum medulla pons midbrain pituitary gland hypothalamus amygdala thalamus choroid plexus choroid plexus corpus callosum basal ganglia substantia nigra dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe caudate hippocampus retina retina

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas
KEGG BRITE Database
Orthology
K10067
Name
pulmonary surfactant-associated protein A
References
Disease
Disease Ontology
Displaying entries 21 - 30 of 86 in total
DO ID Disease Name Source
DOID:12716 newborn respiratory distress syndrome
DOID:1273 respiratory syncytial virus infectious disease
DOID:1287 cardiovascular system disease
DOID:13166 allergic bronchopulmonary aspergillosis
DOID:1324 lung cancer
DOID:1325 bronchus cancer
DOID:13976 peptic esophagitis
DOID:14159 obstructive hydrocephalus
DOID:14265 pulmonary valve insufficiency
DOID:14524 senile degeneration of brain
The Human Phenotype Ontology
Displaying entries 11 - 17 of 17 in total
HPO ID HPO Term
HP:0006519 Alveolar cell carcinoma
HP:0006530 Abnormal pulmonary interstitial morphology
HP:0010444 Pulmonary insufficiency
HP:0010702 Increased circulating antibody level
HP:0012378 Fatigue
HP:0012735 Cough
HP:0100759 Clubbing of fingers
Displaying all 2 entries
Disease ID Disease Name
OMIM:178500
  • interstitial lung disease 2
ORPHA:2032
  • interstitial lung disease 2
PubChem Disease
MedGen Diseases
OMIM Phenotypes
KEGG Diseases
Gene-Disease-Co-Occurrences-in-Literature (PubChem)
Ortholog
Displaying entries 31 - 40 of 43 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
105997599 DIPOR17817
100757798 CRIGR14359
20387 MGI:109518 MOUSE14335
24773 RGD:3665 RATNO10745
100135615 CAVPO18491
101565556 OCTDE19416
103667863 URSMA03730
102026243 CHILA21405
110201595 PHACI27006
101611105 JACJA09414
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024