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Standards Ontologies Notations
surfactant protein A2

Summary
Gene Symbol
  • SFTPA2
Aliases
  • COLEC5
  • SP-A2
  • surfactant, pulmonary-associated protein A2A
Organism
Homo sapiens (human)
External Links
NCBI Gene
729238
HGNC
10799
KEGG Gene ID
hsa:729238
PubChem
729238
Alliance of Genome Resources
Annotation
Keyword
  • Acetylation
  • Calcium
  • Collagen
  • Disease variant
  • Disulfide bond
  • Extracellular matrix
  • Glycoprotein
  • Hydroxylation
  • Lectin
  • Reference proteome
  • Signal
  • Surface film
Proteins
Displaying 1 entry
UniProt Protein Name
Q8IWL1
  • 35 kDa pulmonary surfactant-associated protein
  • Alveolar proteinosis protein
  • Collectin-5
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 7 in total
GO Term Evidence Code PMID
lamellar body
collagen trimer
extracellular region
endoplasmic reticulum membrane
multivesicular body
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
Human Protein Atlas
ENSG00000185303

soft tissue soft tissue blood blood blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node kidney kidney adrenal gland adrenal gland breast breast duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland nasopharynx nasopharynx tongue tonsil tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder ductus deferens ductus deferens seminal vesicle seminal vesicle seminal vesicle seminal vesicle testis testis epididymis epididymis brain smooth muscle urinary bladder prostate bone marrow skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus cartilage sole of foot sole of foot soft tissue blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lactating breast lactating breast kidney kidney adrenal gland adrenal gland duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland salivary gland salivary gland salivary gland salivary gland salivary gland nasopharynx tongue tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder brain skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus smooth muscle urinary bladder vagina ovary ovary fallopian tube fallopian tube endometrium placenta cervix cervix bone marrow cartilage sole of foot sole of foot olfactory region cerebral cortex cerebellum medulla pons midbrain pituitary gland hypothalamus amygdala thalamus choroid plexus choroid plexus corpus callosum basal ganglia substantia nigra dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe caudate hippocampus retina retina

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas
KEGG BRITE Database
Orthology
K10067
Name
pulmonary surfactant-associated protein A
References
Disease
Disease Ontology
Displaying entries 31 - 40 of 86 in total
DO ID Disease Name Source
DOID:14557 primary pulmonary hypertension
DOID:1485 cystic fibrosis
DOID:1573 communicating hydrocephalus
DOID:162 cancer
DOID:1682 congenital heart disease
DOID:1749 squamous cell carcinoma
DOID:1936 atherosclerosis
DOID:2018 hyperinsulinism
DOID:2247 spondylosis
DOID:2320 obstructive lung disease
The Human Phenotype Ontology
Displaying entries 1 - 10 of 17 in total
HPO ID HPO Term
HP:0000006 Autosomal dominant inheritance
HP:0001063 Acrocyanosis
HP:0001394 Cirrhosis
HP:0002020 Gastroesophageal reflux
HP:0002092 Pulmonary arterial hypertension
HP:0002094 Dyspnea
HP:0002110 Bronchiectasis
HP:0002206 Pulmonary fibrosis
HP:0002875 Exertional dyspnea
HP:0003546 Exercise intolerance
Displaying all 2 entries
Disease ID Disease Name
OMIM:178500
  • interstitial lung disease 2
ORPHA:2032
  • interstitial lung disease 2
PubChem Disease
MedGen Diseases
OMIM Phenotypes
KEGG Diseases
Gene-Disease-Co-Occurrences-in-Literature (PubChem)
Ortholog
Displaying entries 21 - 30 of 43 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
112928435 VULVU02021
101672376 MUSPF07914
101101085 FELCA26287
101326351 TURTR02103
118882259 BALMU15433
100033826 HORSE15033
397503 PIGXX07906
407213 BOVIN22632
102175746 CAPHI18552
443033 SHEEP12935
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024