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complement C7

Summary

Gene Symbol

Organism

Homo sapiens (human)

External Links

NCBI Gene

730

PubChem

730

Alliance of Genome Resources

HGNC:1346

Annotation

Keyword

3D-structure
Complement alternate pathway
Direct protein sequencing
Disease variant
Disulfide bond
EGF-like domain
Glycoprotein
Membrane attack complex
Reference proteome
Repeat
Secreted
Signal
Sushi

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q05CI3
P10643

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
complement activation	IBA
complement activation, alternative pathway	IEA
complement activation, classical pathway	IEA
killing of cells of another organism	IEA
positive regulation of immune response	NAS	30552328

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

complement activation

activation of immune response [inference]

complement activation

immune response [inference]

humoral immune response [inference]

complement activation

innate immune response [inference]

complement activation, alternative pathway

cellular process [inference]

cell killing [inference]

killing of cells of another organism

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

complement activation, alternative pathway

disruption of anatomical structure in another organism [inference]

disruption of cell in another organism [inference]

killing of cells of another organism

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response [inference]

complement activation, alternative pathway

immune response [inference]

humoral immune response [inference]

complement activation

innate immune response [inference]

complement activation, alternative pathway

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

complement activation, alternative pathway

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

complement activation, alternative pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response

activation of immune response [inference]

complement activation

regulation of immune response [inference]

positive regulation of immune response

activation of immune response [inference]

complement activation

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response

activation of immune response [inference]

complement activation

positive regulation of response to stimulus [inference]

positive regulation of immune response

activation of immune response [inference]

complement activation

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response

activation of immune response [inference]

complement activation

regulation of immune response [inference]

positive regulation of immune response

activation of immune response [inference]

complement activation

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GO Term	Evidence Code	PMID
extracellular region	TAS
membrane attack complex	IDA	22832194
membrane attack complex	IBA
membrane attack complex	IPI	30552328
extracellular space	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

pore complex [inference]

membrane attack complex

plasma membrane protein complex [inference]

membrane attack complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

potassium transporter

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060300	complement component 7 deficiency	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	730	Xenbase:XB-GENE-5894898
Mus musculus	109828	Xenbase:XB-GENE-5894898	MOUSE15016
Sus scrofa	397526		PIGXX10535
Canis lupus familiaris	489221		CANLF14988
Bos taurus	507339		BOVIN16004
Macaca mulatta	696926		MACMU37771
Pan troglodytes	738238		PANTR35650
Monodelphis domestica	100018307		MONDO18251
Ornithorhynchus anatinus	100088665		ORNAN18709
Pongo abelii	100172681		PONAB29278

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements