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Submissions

aconitate decarboxylase 1

Summary

Gene Symbol

ACOD1

Aliases

Organism

Homo sapiens (human)

External Links

NCBI Gene

730249

HGNC

33904

KEGG Gene ID

hsa:730249

PubChem

730249

Alliance of Genome Resources

HGNC:33904

Annotation

Keyword

3D-structure
Antimicrobial
Inflammatory response
Innate immunity
Lyase
Mitochondrion
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
A6NK06	Aconitate decarboxylase Aconitate decarboxylase 1 Cis-aconitic acid decarboxylase Immune-responsive gene 1 protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	PMID
positive regulation of antimicrobial humoral response	IDA	23610393
defense response	IDA	23610393
defense response	IBA
inflammatory response	IEA
embryo implantation	ISS

GO Hierarchy

biological process

immune system process [inference]

tolerance induction [inference]

tolerance induction to lipopolysaccharide

cellular process [inference]

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

cellular response to cytokine stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to ketone [inference]

cellular response to progesterone stimulus

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin

cellular response to lipopolysaccharide

reproductive process [inference]

embryo implantation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to stimulus [inference]

response to stress [inference]

defense response

inflammatory response

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin

cellular response to lipopolysaccharide

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin

cellular response to lipopolysaccharide

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin

cellular response to lipopolysaccharide

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

response to steroid hormone [inference]

response to progesterone [inference]

cellular response to progesterone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

response to chemical [inference]

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin

cellular response to lipopolysaccharide

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

response to steroid hormone [inference]

response to progesterone [inference]

cellular response to progesterone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

response to organic cyclic compound [inference]

response to steroid hormone [inference]

response to progesterone [inference]

cellular response to progesterone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

response to lipid [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

response to steroid hormone [inference]

response to progesterone [inference]

cellular response to progesterone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

response to cytokine [inference]

response to type II interferon [inference]

cellular response to type II interferon

response to tumor necrosis factor [inference]

cellular response to tumor necrosis factor

response to interferon-beta [inference]

cellular response to interferon-beta

response to interleukin-1 [inference]

cellular response to interleukin-1

cellular response to cytokine stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

cellular response to cytokine stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

response to ketone [inference]

response to progesterone [inference]

cellular response to progesterone stimulus

cellular response to ketone [inference]

cellular response to progesterone stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

cellular response to cytokine stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to ketone [inference]

cellular response to progesterone stimulus

response to oxygen-containing compound [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

response to ketone [inference]

response to progesterone [inference]

cellular response to progesterone stimulus

cellular response to ketone [inference]

cellular response to progesterone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to ketone [inference]

cellular response to progesterone stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

cellular response to cytokine stimulus [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to progesterone stimulus

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to ketone [inference]

cellular response to progesterone stimulus

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin

cellular response to lipopolysaccharide

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

positive regulation of humoral immune response [inference]

positive regulation of antimicrobial humoral response

regulation of immune response [inference]

regulation of humoral immune response [inference]

regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial humoral response

positive regulation of humoral immune response [inference]

positive regulation of antimicrobial humoral response

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of immune response [inference]

negative regulation of innate immune response

positive regulation of immune response [inference]

positive regulation of humoral immune response [inference]

positive regulation of antimicrobial humoral response

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of type I interferon production [inference]

negative regulation of type I interferon production

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

positive regulation of metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of type I interferon production [inference]

negative regulation of type I interferon production

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species metabolic process

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of type I interferon production [inference]

negative regulation of type I interferon production

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

regulation of lipopolysaccharide-mediated signaling pathway [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

positive regulation of humoral immune response [inference]

positive regulation of antimicrobial humoral response

positive regulation of metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of antimicrobial humoral response

positive regulation of defense response [inference]

positive regulation of antimicrobial humoral response

positive regulation of response to external stimulus [inference]

positive regulation of antimicrobial humoral response

positive regulation of immune response [inference]

positive regulation of humoral immune response [inference]

positive regulation of antimicrobial humoral response

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

negative regulation of innate immune response

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

negative regulation of defense response [inference]

negative regulation of response to external stimulus [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

negative regulation of immune response [inference]

negative regulation of innate immune response

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial humoral response

negative regulation of response to biotic stimulus [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

negative regulation of innate immune response

positive regulation of response to biotic stimulus [inference]

positive regulation of antimicrobial humoral response

regulation of lipopolysaccharide-mediated signaling pathway [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

regulation of lipopolysaccharide-mediated signaling pathway [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of response to external stimulus [inference]

regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial humoral response

regulation of lipopolysaccharide-mediated signaling pathway [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

negative regulation of response to external stimulus [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

positive regulation of response to external stimulus [inference]

positive regulation of antimicrobial humoral response

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of inflammatory response [inference]

negative regulation of inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of antimicrobial humoral response

positive regulation of defense response [inference]

positive regulation of antimicrobial humoral response

positive regulation of response to external stimulus [inference]

positive regulation of antimicrobial humoral response

positive regulation of immune response [inference]

positive regulation of humoral immune response [inference]

positive regulation of antimicrobial humoral response

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

negative regulation of innate immune response

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

negative regulation of defense response [inference]

negative regulation of response to external stimulus [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of immune response [inference]

regulation of humoral immune response [inference]

regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial humoral response

positive regulation of humoral immune response [inference]

positive regulation of antimicrobial humoral response

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of immune response [inference]

negative regulation of innate immune response

positive regulation of immune response [inference]

positive regulation of humoral immune response [inference]

positive regulation of antimicrobial humoral response

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of antimicrobial humoral response [inference]

positive regulation of antimicrobial humoral response

negative regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of antimicrobial humoral response

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of inflammatory response [inference]

negative regulation of inflammatory response

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

regulation of lipopolysaccharide-mediated signaling pathway [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 2 signaling pathway [inference]

negative regulation of toll-like receptor 2 signaling pathway

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of type I interferon production [inference]

negative regulation of type I interferon production

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species metabolic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway [inference]

tolerance induction to lipopolysaccharide

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of type I interferon production [inference]

negative regulation of type I interferon production

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

regulation of DNA-binding transcription factor activity [inference]

negative regulation of DNA-binding transcription factor activity [inference]

negative regulation of NF-kappaB transcription factor activity

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mitochondrion	ISS
mitochondrion	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein homodimerization activity	IDA	31548418
aconitate decarboxylase activity	IDA	23610393 31548418 35662396
aconitate decarboxylase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-carbon lyase activity [inference]

carboxy-lyase activity [inference]

aconitate decarboxylase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

aconitate decarboxylase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
aconitate decarboxylase activity
lyase activity

Displaying **all 6** entries
InterPro
MmgE/PrpD superfamily, domain 1
MmgE/PrpD superfamily, domain 2
MmgE/PrpD superfamily
MmgE/PrpD, C-terminal
MmgE/PrpD, N-terminal
MmgE/PrpD

KEGG BRITE Database

Orthology

K17724

Name

aconitate decarboxylase [EC:4.1.1.6]

References

23610393

Rhea

RHEA:15253

H⁺ + cis-aconitate

CO₂ + itaconate

Enzyme

4.1.1.6

PMID

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	16365		MOUSE12470
Rattus norvegicus	306127		RATNO10024
Canis lupus familiaris	485496		CANLF08764
Macaca mulatta	695991		MACMU17039
Xenopus tropicalis	730249	Xenbase:XB-GENE-22169773
Danio rerio	795305		DANRE44972
Monodelphis domestica	100012559		MONDO31275
Equus caballus	100052594		HORSE12850
Ornithorhynchus anatinus	100088444		ORNAN14982
Oryctolagus cuniculus	100343808		RABIT12508

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements