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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
complement C8 beta chain
Summary
- Gene Symbol
-
- C8B
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Complement alternate pathway
- Direct protein sequencing
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Membrane attack complex
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Signal
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of immune response | ||
| complement activation, alternative pathway | ||
| killing of cells of another organism | ||
| innate immune response |
|
|
| immune response |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| membrane attack complex | ||
| extracellular vesicle | ||
| plasma membrane | ||
| extracellular region |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein-containing complex binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- uncharacterized protein
- Functional Category
-
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
- X: Mobilome: prophages, transposons
| Gene Ontology |
|---|
| complement activation, classical pathway |
| complement activation |
| immune response |
| immune system process |
| InterPro |
|---|
| Low-density lipoprotein (LDL) receptor class A repeat |
| Membrane attack complex component/perforin (MACPF) domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060302 | type II complement component 8 deficiency | |
| DOID:5844 | myocardial infarction |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 110382 | MGI:88236 | MOUSE41884 | ||
| 313421 | RGD:2239 | RATNO33738 | ||
| 456887 | 9598_0:0006a2 | PANTR21215 | ||
| 479555 | CANLF15663 | |||
| 513217 | BOVIN26860 | |||
| 716155 | MACMU24082 | |||
| 793127 | ZFIN:ZDB-GENE-070912-163 | DANRE30179 | ||
| 100037954 | PIGXX30289 | |||
| 100059423 | HORSE26947 | |||
| 100222207 | TAEGU29316 |
