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CD70 molecule

Summary

Gene Symbol

CD70

Organism

Sus scrofa (pig)

External Links

NCBI Gene: 733577
PubChem: 733577

Annotation

Keyword

Cell membrane
Disulfide bond
Glycoprotein
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q3ZDR4	CD27 ligand

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
tumor necrosis factor-mediated signaling pathway	IEA	30032202
T cell activation
immune response	IEA	22301074
adaptive immune memory response involving T cells and B cells

GO Hierarchy

biological process

immune system process [inference]

immune response

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

adaptive immune memory response involving T cells and B cells

adaptive immune memory response [inference]

adaptive immune memory response involving T cells and B cells

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation

immunological memory process [inference]

adaptive immune memory response [inference]

adaptive immune memory response involving T cells and B cells

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

tumor necrosis factor-mediated signaling pathway

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation

response to stimulus [inference]

immune response

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

adaptive immune memory response involving T cells and B cells

adaptive immune memory response [inference]

adaptive immune memory response involving T cells and B cells

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

tumor necrosis factor-mediated signaling pathway

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA	30032202
extracellular exosome	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
tumor necrosis factor receptor binding	IEA	22301074 30032202
receptor ligand activity

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

cytokine receptor binding [inference]

tumor necrosis factor receptor superfamily binding [inference]

tumor necrosis factor receptor binding

receptor ligand activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

CD70

Functional Category

L: Replication, recombination and repair
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
immune response
tumor necrosis factor receptor binding
tumor necrosis factor-mediated signaling pathway

Displaying **all 3** entries
InterPro
CD70 antigen
Tumour necrosis factor domain
Tumour necrosis factor-like domain superfamily

Ortholog

Displaying entries **1 - 10** of 52 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Homo sapiens	970		HUMAN40166
Mus musculus	21948		MOUSE20346
Rattus norvegicus	301132		RATNO43808
Bos taurus	522074	9913_0:001914	BOVIN32795
Macaca mulatta	701080		MACMU20795
Equus caballus	100065854		HORSE40371
Callithrix jacchus	100399409		CALJA23859
Pongo abelii	100444685		PONAB15093
Ailuropoda melanoleuca	100475352		AILME04010
Nomascus leucogenys	100595486		NOMLE00332

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements