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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
uncoupling protein 3
Summary
- Gene Symbol
-
- UCP3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Diabetes mellitus
- Disease variant
- Mitochondrion inner membrane
- Obesity
- Reference proteome
- Repeat
- Transmembrane helix
- Transport
- Proteins
| UniProt | Protein Name |
|---|---|
| P55916 |
|
| A0A0S2Z4G5 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to fenofibrate | ||
| response to superoxide | ||
| response to insulin | ||
| response to hypoxia | ||
| response to nutrient |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitochondrial inner membrane | ||
| mitochondrion |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| oxidative phosphorylation uncoupler activity | ||
| calcium ion transmembrane transporter activity | ||
| proton transmembrane transporter activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- mitochondrial carrier
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- K: Transcription
- T: Signal transduction mechanisms
| InterPro |
|---|
| Mitochondrial carrier domain superfamily |
| Mitochondrial substrate/solute carrier |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10763 | hypertension | |
| DOID:11716 | prediabetes syndrome | |
| DOID:1459 | hypothyroidism | |
| DOID:4247 | coronary restenosis | |
| DOID:6000 | congestive heart failure | |
| DOID:7998 | hyperthyroidism | |
| DOID:9351 | diabetes mellitus | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9743 | diabetic neuropathy | |
| DOID:9970 | obesity |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 22229 | MGI:1099787 | MOUSE55493 | ||
| 25708 | RGD:3933 | RATNO18311 | ||
| 281563 | BOVIN07215 | |||
| 397116 | PIGXX34981 | |||
| 403575 | CANLF08278 | |||
| 443278 | SHEEP06492 | |||
| 476808 | CANLF08278 | |||
| 574125 | MACMU11236 | |||
| 619390 | MONDO24683 | |||
| 748551 | 9598_0:002e79 | PANTR03808 |
