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UDP glucuronosyltransferase family 2 member B7

Summary

Gene Symbol

UGT2B7

Aliases

UGT2B9

Organism

Homo sapiens (human)

External Links

NCBI Gene

7364

HGNC

12554

KEGG Gene ID

hsa:7364

PubChem

7364

Alliance of Genome Resources

HGNC:12554

Annotation

Keyword

3D-structure
Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Proteomics identification
Reference proteome
Signal
Steroid metabolism
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P16662	3,4-catechol estrogen-specific UDPGT UDP-glucuronosyltransferase 2B9 UDPGTh-2
E9PBP8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
lipid metabolic process	TAS	2159463
cellular glucuronidation	IBA IDA	17442341 18719240 20056724 22579593
androgen metabolic process	IDA	17442341
xenobiotic metabolic process	TAS
estrogen metabolic process	IBA IDA	18719240

GO Hierarchy

biological process

metabolic process [inference]

hormone metabolic process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

xenobiotic metabolic process

primary metabolic process [inference]

lipid metabolic process

steroid metabolic process [inference]

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

lipid metabolic process

steroid metabolic process [inference]

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

xenobiotic metabolic process

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	TAS
membrane	TAS	2159463

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
retinoic acid binding	IDA	20308471
glucuronosyltransferase activity	IBA IDA TAS	17442341 18052087 18719240 20056724 22579593

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

glucuronosyltransferase activity

hexosyltransferase activity [inference]

glucuronosyltransferase activity

binding [inference]

lipid binding [inference]

isoprenoid binding [inference]

retinoid binding [inference]

retinoic acid binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

retinoic acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

retinoic acid binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00699

Name

glucuronosyltransferase [EC:2.4.1.17]

References

Rhea

RHEA:21032

glucuronate acceptor + UDP-α-D-glucuronate

acceptor β-D-glucuronoside + H⁺ + UDP

Enzyme

2.4.1.17

PMID

Disease

Disease Ontology

Displaying entries **1 - 10** of 36 in total

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DO ID	Disease Name	Source
DOID:0060262	gallbladder disease	DisGeNET
DOID:0080199	colorectal carcinoma	DisGeNET
DOID:10548	cardia cancer	DisGeNET
DOID:10923	sickle cell anemia	DisGeNET
DOID:11054	urinary bladder cancer	DisGeNET DisGeNET DisGeNET
DOID:114	heart disease	DisGeNET
DOID:11832	visual epilepsy	DisGeNET
DOID:1287	cardiovascular system disease	DisGeNET
DOID:13250	diarrhea	DisGeNET
DOID:1380	endometrial cancer	DisGeNET DisGeNET

Ortholog

Displaying entries **1 - 10** of 85 in total

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Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	172087	WB:WBGene00015692
Caenorhabditis elegans	175591	WB:WBGene00010904
Caenorhabditis elegans	178581	WB:WBGene00021709
Caenorhabditis elegans	178883	WB:WBGene00020587
Caenorhabditis elegans	179406	WB:WBGene00007422
Caenorhabditis elegans	179446	WB:WBGene00007070
Caenorhabditis elegans	179449	WB:WBGene00007072
Caenorhabditis elegans	181205	WB:WBGene00007650
Caenorhabditis elegans	182143	WB:WBGene00015371
Caenorhabditis elegans	182814	WB:WBGene00016013

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements