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arylsulfatase G

Summary

Gene Symbol

Arsg

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

74008

PubChem

74008

Alliance of Genome Resources

MGI:1921258

Annotation

Keyword

Alternative splicing
Calcium
Disulfide bond
Glycoprotein
Hydrolase
Lysosome
Metal-binding
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q3TYD4	N-sulfoglucosamine-3-sulfatase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
sulfur compound metabolic process	ISO
sulfur compound metabolic process	IEA
lysosome organization	IMP	26975023
glial cell differentiation	IMP	26975023
gene expression	IMP	26975023

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

sulfur compound metabolic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

neuron apoptotic process

cellular metabolic process [inference]

sulfur compound metabolic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular developmental process [inference]

cell differentiation [inference]

glial cell differentiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vacuole organization [inference]

lytic vacuole organization [inference]

lysosome organization

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells

developmental process [inference]

anatomical structure development [inference]

retina development in camera-type eye

cellular developmental process [inference]

cell differentiation [inference]

glial cell differentiation

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells

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GO Term	Evidence Code	PMID
extracellular space	ISO
extracellular space	IEA
lysosome	ISS
lysosome	ISO
lysosome	IDA	25135642

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum

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GO Term	Evidence Code	PMID
arylsulfatase activity	ISS
arylsulfatase activity	ISO
arylsulfatase activity	IDA	25135642
arylsulfatase activity	IBA
N-sulfoglucosamine-3-sulfatase activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

sulfuric ester hydrolase activity [inference]

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

arylsulfatase i

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
sulfuric ester hydrolase activity

Displaying **all 3** entries
InterPro
Alkaline-phosphatase-like, core domain superfamily
Sulfatase, N-terminal
Sulfatase, conserved site

Rhea

RHEA:17261

an aryl sulfate + H₂O

H⁺ + sulfate + a phenol

Enzyme

3.1.6.1

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:12798	mucopolysaccharidosis	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP002969
Gene Name: arylsulfatase G

Ortholog

Displaying entries **21 - 30** of 92 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	791159	WB:WBGene00006309
Monodelphis domestica	100029210		MONDO09856
Equus caballus	100062864		HORSE04345
Taeniopygia guttata	100232718		TAEGU07274
Oryctolagus cuniculus	100340274		RABIT07905
Callithrix jacchus	100400154		CALJA35313
Pongo abelii	100447099		PONAB11917
Ailuropoda melanoleuca	100475746		AILME06185
Meleagris gallopavo	100546213		MELGA06723
Anolis carolinensis	100555681		ANOCA16215

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GlyComb

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UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements