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ubiquitously transcribed tetratricopeptide repeat containing, Y-linked

Summary

Gene Symbol

UTY

Organism

Homo sapiens (human)

External Links

NCBI Gene

7404

PubChem

7404

Alliance of Genome Resources

HGNC:12638

Annotation

Keyword

3D-structure
Alternative splicing
Chromatin regulator
Dioxygenase
Direct protein sequencing
Iron
Metal-binding
Nucleus
Oxidoreductase
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
TPR repeat
Zinc

Proteins

Displaying entries **1 - 10** of 28 in total

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UniProt	Protein Name
F4MH92
F4MH60
E1U1M3
F4MH31
F4MH91
F4MH62
O14607	Ubiquitously-transcribed TPR protein on the Y chromosome Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein [histone H3]-trimethyl-L-lysine(27) demethylase UTY
F4MH35
F4MH32
F4MH50

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
heart development	IBA
regulation of gene expression	IBA
chromatin remodeling	IEA

GO Hierarchy

biological process

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

heart development

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

Displaying **all 2** entries
GO Term	Evidence Code	PMID
nucleoplasm	TAS
MLL3/4 complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

histone methyltransferase complex [inference]

MLL3/4 complex

catalytic complex [inference]

transferase complex [inference]

methyltransferase complex [inference]

histone methyltransferase complex [inference]

MLL3/4 complex

cellular anatomical entity [inference]

nucleoplasm

Displaying **all 5** entries
GO Term	Evidence Code	PMID
RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
histone demethylase activity	TAS
histone H3K27me2/H3K27me3 demethylase activity	IBA
metal ion binding	IEA
chromatin DNA binding	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

2-oxoglutarate-dependent dioxygenase activity [inference]

histone H3K27me2/H3K27me3 demethylase activity

dioxygenase activity [inference]

2-oxoglutarate-dependent dioxygenase activity [inference]

histone H3K27me2/H3K27me3 demethylase activity

demethylase activity [inference]

protein demethylase activity [inference]

histone demethylase activity

histone H3 demethylase activity [inference]

histone H3K27me2/H3K27me3 demethylase activity

catalytic activity, acting on a protein [inference]

protein demethylase activity [inference]

histone demethylase activity

histone H3 demethylase activity [inference]

histone H3K27me2/H3K27me3 demethylase activity

histone modifying activity [inference]

histone demethylase activity

histone H3 demethylase activity [inference]

histone H3K27me2/H3K27me3 demethylase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

chromatin binding [inference]

chromatin DNA binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

transcription regulatory region nucleic acid binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

DNA binding [inference]

double-stranded DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

chromatin DNA binding

sequence-specific DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0060473	Kabuki syndrome	Alliance of Genome Resources
DOID:1574	alcohol use disorder	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 44 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	22290	MGI:894810
Drosophila melanogaster	34377	FB:FBgn0260749
Pan troglodytes	449579		PANTR47329
Danio rerio	569207	ZFIN:ZDB-GENE-070112-2002	DANRE38740
Danio rerio	569277	ZFIN:ZDB-GENE-081105-56	DANRE44687
Saccharomyces cerevisiae S288C	852410	SGD:S000000316
Xenopus tropicalis	100170558	Xenbase:XB-GENE-960316
Macaca mulatta	100270704		MACMU48742
Oreochromis niloticus	100712385		ORENI21594
Takifugu rubripes	101067688		TAKRU47625