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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
vascular endothelial growth factor A
Summary
- Gene Symbol
-
- VEGFA
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative initiation
- Alternative promoter usage
- Alternative splicing
- Angiogenesis
- Cytoplasm
- Developmental protein
- Differentiation
- Direct protein sequencing
- Disulfide bond
- Endoplasmic reticulum
- Extracellular matrix
- Glycoprotein
- Golgi apparatus
- Growth factor
- Heparin-binding
- Mitogen
- Nucleus
- Proteomics identification
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A0Y0IMM4 |
|
| P15692 |
|
| A2A2V4 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of cell population proliferation | ||
| cell-cell adhesion | ||
| positive regulation of cell division | ||
| vascular wound healing | ||
| lymphangiogenesis |
GO Hierarchy
- positive regulation of vascular endothelial growth factor signaling pathway
- regulation of nitric oxide mediated signal transduction
- positive regulation of vascular endothelial growth factor signaling pathway
- positive regulation of vascular endothelial growth factor signaling pathway
- positive regulation of vascular endothelial growth factor signaling pathway
- positive regulation of cell division
- positive regulation of vascular endothelial growth factor signaling pathway
- positive regulation of vascular endothelial growth factor signaling pathway
- regulation of nitric oxide mediated signal transduction
- positive regulation of vascular endothelial growth factor signaling pathway
- positive regulation of vascular endothelial growth factor signaling pathway
- regulation of nitric oxide mediated signal transduction
- positive regulation of vascular endothelial growth factor signaling pathway
- positive regulation of vascular endothelial growth factor signaling pathway
- positive regulation of cell division
biological process
cellular process [inference]
signal transduction [inference]
multicellular organismal process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of nitrogen compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
negative regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signal transduction [inference]
positive regulation of intracellular signal transduction [inference]
regulation of intracellular signal transduction [inference]
regulation of MAPK cascade [inference]
positive regulation of intracellular signal transduction [inference]
positive regulation of signaling [inference]
positive regulation of signal transduction [inference]
positive regulation of intracellular signal transduction [inference]
regulation of localization [inference]
regulation of growth [inference]
regulation of locomotion [inference]
positive regulation of locomotion [inference]
regulation of cell motility [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of signaling [inference]
positive regulation of signal transduction [inference]
positive regulation of intracellular signal transduction [inference]
positive regulation of locomotion [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of signal transduction [inference]
positive regulation of intracellular signal transduction [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cell motility [inference]
positive regulation of response to stimulus [inference]
positive regulation of signal transduction [inference]
positive regulation of intracellular signal transduction [inference]
positive regulation of developmental process [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
positive regulation of signal transduction [inference]
positive regulation of intracellular signal transduction [inference]
regulation of intracellular signal transduction [inference]
regulation of MAPK cascade [inference]
positive regulation of intracellular signal transduction [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
positive regulation of signal transduction [inference]
positive regulation of intracellular signal transduction [inference]
regulation of developmental process [inference]
regulation of anatomical structure morphogenesis [inference]
regulation of cell differentiation [inference]
positive regulation of developmental process [inference]
regulation of multicellular organismal development [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of signal transduction [inference]
positive regulation of intracellular signal transduction [inference]
regulation of intracellular signal transduction [inference]
regulation of MAPK cascade [inference]
positive regulation of intracellular signal transduction [inference]
positive regulation of cell communication [inference]
positive regulation of signal transduction [inference]
positive regulation of intracellular signal transduction [inference]
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of cell population proliferation [inference]
regulation of cellular component biogenesis [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of signal transduction [inference]
positive regulation of intracellular signal transduction [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cell motility [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
regulation of epithelial cell migration [inference]
positive regulation of multicellular organismal process [inference]
regulation of multicellular organismal development [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular matrix | ||
| membrane | ||
| platelet alpha granule lumen | ||
| Golgi apparatus | ||
| secretory granule |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| neuropilin binding | ||
| protein binding | ||
| heparin binding | ||
| vascular endothelial growth factor receptor binding | ||
| platelet-derived growth factor receptor binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Vascular endothelial growth factor
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| Cystine-knot cytokine |
| PDGF/VEGF domain |
| Platelet-derived growth factor, conserved site |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0002116 | pterygium | |
| DOID:0050185 | erythema multiforme | |
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050852 | limb ischemia | |
| DOID:0060074 | ductal carcinoma in situ | |
| DOID:0060108 | brain glioma | |
| DOID:0060181 | ischemic colitis | |
| DOID:0060193 | amyotrophic lateral sclerosis type 1 | |
| DOID:0060224 | atrial fibrillation | |
| DOID:0060643 | primary sclerosing cholangitis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 22339 | MGI:103178 | |||
| 30682 | ZFIN:ZDB-GENE-990415-273 | |||
| 83785 | RGD:619991 | RATNO42403 | ||
| 281572 | BOVIN18562 | |||
| 373589 | Xenbase:XB-GENE-6253057 | |||
| 493845 | FELCA12631 | |||
| 558154 | ZFIN:ZDB-GENE-030131-4605 | |||
| 574209 | MACMU34310 | |||
| 736875 | 9598_0:001cc8 | |||
| 100037058 | Xenbase:XB-GENE-865061 |
