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sperm acrosome associated 3

Summary

Gene Symbol

Spaca3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

75622

PubChem

75622

Alliance of Genome Resources

MGI:1922872

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasmic vesicle
Disulfide bond
Reference proteome
Secreted
Signal
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A077S9M6
Q9D9X8	Lysozyme-like protein 3 Sperm lysozyme-like protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
fusion of sperm to egg plasma membrane involved in single fertilization	ISO
fusion of sperm to egg plasma membrane involved in single fertilization	IMP	15982649
fusion of sperm to egg plasma membrane involved in single fertilization	IBA
sperm-egg recognition	IMP	15982649

GO Hierarchy

biological process

cellular process [inference]

cell recognition [inference]

cell-cell recognition [inference]

sperm-egg recognition

cellular process involved in reproduction in multicellular organism [inference]

fusion of sperm to egg plasma membrane involved in single fertilization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

plasma membrane organization [inference]

plasma membrane fusion [inference]

fusion of sperm to egg plasma membrane involved in single fertilization

membrane fusion [inference]

plasma membrane fusion [inference]

fusion of sperm to egg plasma membrane involved in single fertilization

reproductive process [inference]

cellular process involved in reproduction in multicellular organism [inference]

fusion of sperm to egg plasma membrane involved in single fertilization

sperm-egg recognition

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
acrosomal vesicle	IDA	15982649
acrosomal vesicle	IBA
acrosomal membrane	ISO
acrosomal membrane	IEA
extracellular region	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane [inference]

acrosomal membrane

bounding membrane of organelle [inference]

secretory granule membrane [inference]

acrosomal membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium [inference]

sperm flagellum

acrosomal matrix

organelle [inference]

membrane-bounded organelle [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium [inference]

sperm flagellum

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

acrosomal vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

acrosomal vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

acrosomal vesicle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
lysozyme activity	IEA
protein binding	IPI	22206759

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

lysozyme activity

peptidoglycan muralytic activity [inference]

lysozyme activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Lysozyme

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
lysozyme activity

Displaying **all 4** entries
InterPro
Glycoside hydrolase family 22 domain
Glycoside hydrolase, family 22, lysozyme
Glycoside hydrolase, family 22
Lysozyme-like domain superfamily

Ortholog

Displaying entries **31 - 40** of 54 in total

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Species	Gene ID	Orthologous MAtrix
Sus scrofa	100415932	PIGXX02854
Pongo abelii	100431905	PONAB12238
Ovis aries	100462675	SHEEP02504
Nomascus leucogenys	100588482	NOMLE16659
Nomascus leucogenys	100597852	NOMLE09366
Cricetulus griseus	100762682	CRIGR01151
Capra hircus	100860900	CAPHI10028
Pan paniscus	100983207	PANPA16994
Papio anubis	101005470	PAPAN13301
Saimiri boliviensis boliviensis	101051411	SAIBB21533