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CDP-L-ribitol pyrophosphorylase A

Summary

Gene Symbol

Crppa

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

75847

PubChem

75847

Alliance of Genome Resources

MGI:1923097

Annotation

Keyword

Alternative splicing
Cytoplasm
Nucleotidyltransferase
Proteomics identification
Reference proteome

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A1Y7VK76	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein Isoprenoid synthase domain-containing protein
A0A1Y7VM96	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein Isoprenoid synthase domain-containing protein
Q5RJG7	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein Isoprenoid synthase domain-containing protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein glycosylation	IMP	23217742
protein O-linked mannosylation	IBA ISO ISS
isoprenoid biosynthetic process	IEA
axon guidance	IMP	23217742

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

biosynthetic process [inference]

cellular biosynthetic process [inference]

isoprenoid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

isoprenoid biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

mannosylation [inference]

protein mannosylation [inference]

protein O-linked mannosylation

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

macromolecule glycosylation [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

isoprenoid biosynthetic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol	IBA ISO ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying **all 3** entries
GO Term	Evidence Code	PMID
D-ribitol-5-phosphate cytidylyltransferase activity	IBA ISO ISS
protein homodimerization activity	ISO ISS
cytidylyltransferase activity	ISO ISS

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity [inference]

cytidylyltransferase activity

D-ribitol-5-phosphate cytidylyltransferase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

D-ribitol-5-phosphate cytidylyltransferase

Functional Category

H: Coenzyme transport and metabolism
I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 4** entries
Gene Ontology
D-ribitol-5-phosphate cytidylyltransferase activity
catalytic activity
cytidylyltransferase activity
protein O-linked mannosylation

Displaying **all 4** entries
InterPro
4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site
Cytidylyltransferase IspD/TarI
D-ribitol-5-phosphate cytidylyltransferase, C-terminal
Nucleotide-diphospho-sugar transferases

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0050560	Walker-Warburg syndrome	Alliance of Genome Resources
DOID:0110295	autosomal recessive limb-girdle muscular dystrophy type 2U	Alliance of Genome Resources
DOID:0111234	congenital muscular dystrophy-dystroglycanopathy A7	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 78 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Rattus norvegicus	493574	10116_1:002546	RGD:1359368	RATNO35992
Xenopus tropicalis	548994		Xenbase:XB-GENE-1014860
Macaca mulatta	714980			MACMU31850
Homo sapiens	729920		HGNC:37276	HUMAN87936
Pan troglodytes	744905			PANTR39748
Danio rerio	798716		ZFIN:ZDB-GENE-061110-16
Equus caballus	100065851			HORSE33072
Oryctolagus cuniculus	100337768			RABIT14426
Callithrix jacchus	100391839			CALJA42914
Pongo abelii	100436260			PONAB33726

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements