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ATP-binding cassette, sub-family C member 3

Summary

Gene Symbol

Abcc3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

76408

PubChem

76408

Alliance of Genome Resources

MGI:1923658

Annotation

Keyword

ATP-binding
Alternative splicing
Cell membrane
Glycoprotein
Lipid transport
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Translocase
Transmembrane helix
Transport

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B2RX12	Canalicular multispecific organic anion transporter 2 Multidrug resistance-associated protein 3
A0A0R4J015

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
transmembrane transport	IBA ISO
monoatomic anion transmembrane transport	ISO
xenobiotic transmembrane transport	IEA ISO
bile acid and bile salt transport	ISO ISS
glucuronoside transport	IEA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

xenobiotic transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic anion transport [inference]

monoatomic anion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport

xenobiotic transport

xenobiotic transmembrane transport

secretion [inference]

canalicular bile acid transport

transmembrane transport

xenobiotic transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport

organic substance transport [inference]

lipid transport [inference]

bile acid and bile salt transport

canalicular bile acid transport

organic anion transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

bile acid and bile salt transport

canalicular bile acid transport

icosanoid transport [inference]

leukotriene transport

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

bile acid and bile salt transport

canalicular bile acid transport

icosanoid transport [inference]

leukotriene transport

organic hydroxy compound transport [inference]

bile acid and bile salt transport

canalicular bile acid transport

carbohydrate derivative transport [inference]

glycoside transport [inference]

glucuronoside transport

Displaying **all 4** entries
GO Term	Evidence Code	PMID
basal plasma membrane	ISO
plasma membrane	IDA ISO	12951053
basolateral plasma membrane	IDA ISO	16225954
membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

plasma membrane region [inference]

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
ATP binding	IEA
ABC-type xenobiotic transporter activity	IEA ISO
xenobiotic transmembrane transporter activity	ISO
ATPase-coupled transmembrane transporter activity	IBA ISO
ABC-type bile acid transporter activity	ISO ISS

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

lipid transporter activity [inference]

bile acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled lipid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

icosanoid transmembrane transporter activity

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

ATPase-coupled organic acid transmembrane transporter activity [inference]

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

bile acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

bile acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity

ATPase-coupled organic acid transmembrane transporter activity [inference]

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled lipid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ABC-type transporter activity [inference]

xenobiotic transmembrane transporter activity

ABC-type xenobiotic transporter activity

icosanoid transmembrane transporter activity

carbohydrate derivative transmembrane transporter activity [inference]

glucuronoside transmembrane transporter activity

organic hydroxy compound transmembrane transporter activity [inference]

bile acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

sulfur compound transmembrane transporter activity [inference]

ABC-type glutathione S-conjugate transporter activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity

ATPase-coupled organic acid transmembrane transporter activity [inference]

ATPase-coupled carboxylic acid transmembrane transporter activity [inference]

ATPase-coupled monocarboxylic acid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ATPase-coupled lipid transmembrane transporter activity [inference]

ABC-type bile acid transporter activity

ABC-type transporter activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying entries **1 - 10** of 11 in total

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DO ID	Disease Name	Source
DOID:0080208	metabolic dysfunction-associated steatotic liver disease	Alliance of Genome Resources
DOID:12308	Dubin-Johnson syndrome	Alliance of Genome Resources
DOID:12700	hyperprolactinemia	Alliance of Genome Resources
DOID:13580	cholestasis	Alliance of Genome Resources
DOID:1793	pancreatic cancer	Alliance of Genome Resources
DOID:2741	bilirubin metabolic disorder	Alliance of Genome Resources
DOID:557	kidney disease	Alliance of Genome Resources
DOID:684	hepatocellular carcinoma	Alliance of Genome Resources
DOID:783	end stage renal disease	Alliance of Genome Resources
DOID:9119	acute myeloid leukemia	Alliance of Genome Resources