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solute carrier family 30 member 1

Summary

Gene Symbol

SLC30A1

Organism

Homo sapiens (human)

External Links

NCBI Gene

7779

PubChem

7779

Alliance of Genome Resources

HGNC:11012

JoGo

SLC30A1

TogoVar

SLC30A1

Annotation

Keyword

3D-structure
Antiport
Cell membrane
Cytoplasm
Cytoplasmic vesicle
Endoplasmic reticulum
Glycoprotein
Golgi apparatus
Metal-binding
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Transmembrane helix
Zinc transport

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9Y6M5	Solute carrier family 30 member 1 Zinc transporter 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 20 in total

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GO Term	Evidence Code	PMID
intracellular zinc ion homeostasis	IBA
detoxification of zinc ion	IBA
defense response to bacterium	IDA	32441444
negative regulation of neurotransmitter secretion	ISS
positive regulation of dendritic spine morphogenesis	IEA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

cadmium ion transmembrane transport

zinc ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

cadmium ion transmembrane transport

zinc ion transmembrane transport

export across plasma membrane [inference]

zinc export across plasma membrane

export from cell [inference]

export across plasma membrane [inference]

zinc export across plasma membrane

multicellular organismal process [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

developmental process [inference]

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

inorganic ion homeostasis [inference]

intracellular zinc ion homeostasis

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to bacterium

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

zinc ion transport

zinc ion transmembrane transport

cadmium ion transport [inference]

cadmium ion transmembrane transport

calcium ion transport [inference]

calcium ion import

monoatomic cation transmembrane transport [inference]

cadmium ion transmembrane transport

zinc ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

cadmium ion transmembrane transport

zinc ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

cadmium ion transmembrane transport

zinc ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

cadmium ion transmembrane transport

zinc ion transmembrane transport

export across plasma membrane [inference]

zinc export across plasma membrane

organic substance transport [inference]

calcium ion transport [inference]

calcium ion import

export from cell [inference]

export across plasma membrane [inference]

zinc export across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion [inference]

negative regulation of neurotransmitter secretion

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

regulation of monoatomic cation transmembrane transport [inference]

regulation of zinc ion transmembrane transport [inference]

regulation of zinc ion transmembrane import [inference]

negative regulation of zinc ion transmembrane import

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

negative regulation of cation transmembrane transport [inference]

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion import

regulation of calcium ion import [inference]

negative regulation of calcium ion import

regulation of zinc ion transport [inference]

regulation of zinc ion transmembrane transport [inference]

regulation of zinc ion transmembrane import [inference]

negative regulation of zinc ion transmembrane import

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

negative regulation of zinc ion transport [inference]

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

regulation of monoatomic cation transmembrane transport [inference]

regulation of zinc ion transmembrane transport [inference]

regulation of zinc ion transmembrane import [inference]

negative regulation of zinc ion transmembrane import

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

negative regulation of cation transmembrane transport [inference]

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion import

negative regulation of zinc ion transport [inference]

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

regulation of secretion [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

regulation of secretion by cell [inference]

regulation of neurotransmitter secretion [inference]

negative regulation of neurotransmitter secretion

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion import

negative regulation of zinc ion transport [inference]

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

negative regulation of neurotransmitter transport [inference]

negative regulation of neurotransmitter secretion

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter secretion [inference]

negative regulation of neurotransmitter secretion

negative regulation of neurotransmitter transport [inference]

negative regulation of neurotransmitter secretion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to membrane [inference]

regulation of postsynaptic density protein 95 clustering

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of dendritic spine development [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion import

negative regulation of zinc ion transport [inference]

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

negative regulation of neurotransmitter transport [inference]

negative regulation of neurotransmitter secretion

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of dendrite morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of dendritic spine morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of dendrite development [inference]

regulation of dendrite morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of dendritic spine development [inference]

positive regulation of dendritic spine morphogenesis

regulation of dendritic spine development [inference]

positive regulation of dendritic spine development [inference]

positive regulation of dendritic spine morphogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion [inference]

negative regulation of neurotransmitter secretion

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

regulation of monoatomic cation transmembrane transport [inference]

regulation of zinc ion transmembrane transport [inference]

regulation of zinc ion transmembrane import [inference]

negative regulation of zinc ion transmembrane import

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

negative regulation of cation transmembrane transport [inference]

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

negative regulation of cellular process [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of zinc ion transmembrane transport [inference]

negative regulation of zinc ion transmembrane import

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendritic spine morphogenesis

regulation of dendrite development [inference]

regulation of dendrite morphogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of dendritic spine morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of organelle organization [inference]

regulation of postsynaptic density organization [inference]

regulation of postsynaptic density protein 95 clustering

regulation of synapse organization [inference]

regulation of postsynapse organization [inference]

regulation of dendritic spine morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of postsynaptic density organization [inference]

regulation of postsynaptic density protein 95 clustering

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to membrane [inference]

regulation of postsynaptic density protein 95 clustering

regulation of secretion by cell [inference]

regulation of neurotransmitter secretion [inference]

negative regulation of neurotransmitter secretion

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis [inference]

positive regulation of dendritic spine morphogenesis

detoxification [inference]

detoxification of zinc ion

detoxification of inorganic compound [inference]

detoxification of cadmium ion

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
Golgi membrane	IEA
cytoplasm	IDA	18158319
endoplasmic reticulum	IDA	18158319
endoplasmic reticulum	IBA
endoplasmic reticulum membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane

nuclear membrane

bounding membrane of organelle [inference]

Golgi membrane

plasma membrane region [inference]

basolateral plasma membrane

synaptic membrane [inference]

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

synapse [inference]

Schaffer collateral - CA1 synapse

T-tubule

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

postsynaptic specialization, intracellular component [inference]

postsynaptic density, intracellular component

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

postsynaptic specialization, intracellular component [inference]

postsynaptic density, intracellular component

postsynaptic specialization [inference]

postsynaptic density [inference]

glutamatergic postsynaptic density

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
zinc ion transmembrane transporter activity	ISS
zinc ion transmembrane transporter activity	TAS
zinc ion transmembrane transporter activity	IBA
protein binding	IPI	18158319 25657003 36204728
calcium channel inhibitor activity	ISS