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Standards Ontologies Notations
Guidelines
MIRAGE
LDL receptor related protein 8

Summary
Gene Symbol
  • LRP8
Organism
Homo sapiens (human)
NCBI Gene
7804
PubChem
7804
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Calcium
  • Cell membrane
  • Disulfide bond
  • EGF-like domain
  • Endocytosis
  • Glycoprotein
  • Host-virus interaction
  • Metal-binding
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Repeat
  • Secreted
  • Signal
  • Transmembrane helix
  • Ubl conjugation
Proteins
Displaying 1 entry
UniProt Protein Name
Q14114
  • Apolipoprotein E receptor 2
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 21 in total
GO Term Evidence Code PMID
retinoid metabolic process
proteolysis
lipid metabolic process
endocytosis
signal transduction
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
dehydrogenase
Functional Category
  • E: Amino acid transport and metabolism
  • G: Carbohydrate transport and metabolism
  • I: Lipid transport and metabolism
Displaying all 4 entries
Gene Ontology
NAD+ binding
fatty acid metabolic process
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
oxidoreductase activity
Displaying all 5 entries
InterPro
3-hydroxyacyl-CoA dehydrogenase, C-terminal
3-hydroxyacyl-CoA dehydrogenase, NAD binding
6-phosphogluconate dehydrogenase, domain 2
6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
NAD(P)-binding domain superfamily
Disease
Disease Ontology
Displaying all 5 entries
DO ID Disease Name Source
DOID:10652 Alzheimer's disease
DOID:1307 dementia
DOID:3393 coronary artery disease
DOID:5419 schizophrenia
DOID:5844 myocardial infarction
Ortholog
Displaying entries 1 - 10 of 58 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
3949 FB:FBgn0051092
7436 FB:FBgn0051092
7804 Xenbase:XB-GENE-980035
16835 FB:FBgn0066101
16975 MOUSE39884
22359 FB:FBgn0066101
174116 Xenbase:XB-GENE-980035
300438 FB:FBgn0066101
362558 RATNO34069
456865 PANTR21143
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025