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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
dual oxidase 2
Summary
- Gene Symbol
-
- Duox2
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Alternative splicing
- Calcium
- Cell junction
- Cell membrane
- Disulfide bond
- FAD
- Glycoprotein
- Hydrogen peroxide
- Metal-binding
- NADP
- Reference proteome
- Repeat
- Signal
- Thyroid hormones biosynthesis
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9ES45 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of cell motility | ||
| hydrogen peroxide biosynthetic process | ||
| bone mineralization | ||
| cuticle development | ||
| multicellular organism growth |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| anchoring junction | ||
| apical plasma membrane | ||
| cell leading edge | ||
| NADPH oxidase complex | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| superoxide-generating NAD(P)H oxidase activity | ||
| peroxidase activity | ||
| NADH oxidase H202-forming activity | ||
| NADPH oxidase H202-forming activity | ||
| heme binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- dual oxidase 2
- Functional Category
-
- C: Energy production and conversion
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050328 | congenital hypothyroidism | |
| DOID:0050338 | primary bacterial infectious disease | |
| DOID:0112189 | thyroid dyshormonogenesis 6 | |
| DOID:1459 | hypothyroidism | |
| DOID:1498 | cholera | |
| DOID:8577 | ulcerative colitis | |
| DOID:8778 | Crohn's disease | |
| DOID:9281 | phenylketonuria |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 100070566 | HORSE16753 | |||
| 100089154 | ORNAN26547 | |||
| 100218721 | TAEGU02071 | |||
| 100345610 | RABIT06101 | |||
| 100387872 | CALJA00223 | |||
| 100445893 | PONAB08903 | |||
| 100462743 | SHEEP18292 | |||
| 100486050 | Xenbase:XB-GENE-6047411 | |||
| 100486194 | Xenbase:XB-GENE-1005876 | |||
| 100538948 | MELGA02946 |
