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solute carrier family 39 member 7

Summary

Gene Symbol

SLC39A7

Organism

Homo sapiens (human)

External Links

NCBI Gene

7922

PubChem

7922

Alliance of Genome Resources

HGNC:4927

Annotation

Keyword

3D-structure
Disease variant
Endoplasmic reticulum
Golgi apparatus
Methylation
Phosphoprotein
Reference proteome
Transmembrane helix
Zinc transport

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A024RCX7	Solute carrier family 39 member 7 Zrt-, Irt-like protein 7
Q92504	Histidine-rich membrane protein Ke4 Really interesting new gene 5 protein Solute carrier family 39 member 7 Zrt-, Irt-like protein 7
B4DZZ8	Solute carrier family 39 member 7 Zrt-, Irt-like protein 7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
skin epidermis development	IEA
zinc ion transmembrane transport	IBA IDA TAS	14525538
intracellular zinc ion homeostasis	IBA IMP	29980658
B cell differentiation	IMP	30718914
regulation of ferroptosis	IMP	33608508

GO Hierarchy

biological process

immune system process [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

B cell activation [inference]

B cell differentiation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

B cell activation [inference]

B cell differentiation

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

zinc ion transmembrane transport

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

B cell activation [inference]

B cell differentiation

developmental process [inference]

anatomical structure development [inference]

tissue development [inference]

epidermis development [inference]

skin epidermis development

epithelium development [inference]

skin epidermis development

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular zinc ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular zinc ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular zinc ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular zinc ion homeostasis

inorganic ion homeostasis [inference]

intracellular zinc ion homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

zinc ion transport [inference]

zinc ion transmembrane transport

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

zinc ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of programmed cell death [inference]

regulation of ferroptosis

Displaying **all 5** entries
GO Term	Evidence Code	PMID
membrane	TAS	8812499
Golgi apparatus	IEA
endoplasmic reticulum membrane	IDA TAS	29980658
nucleoplasm	IDA
endoplasmic reticulum	IDA	14525538 30718914

GO Hierarchy

cellular component

cellular anatomical entity [inference]

nucleoplasm

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	22317921 32296183
zinc ion transmembrane transporter activity	IBA IDA IMP TAS	14525538 30718914

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

transition metal ion transmembrane transporter activity [inference]

zinc ion transmembrane transporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

transition metal ion transmembrane transporter activity [inference]

zinc ion transmembrane transporter activity

salt transmembrane transporter activity [inference]

zinc ion transmembrane transporter activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

transporter

Functional Category

M: Cell wall/membrane/envelope biogenesis
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
metal ion transmembrane transporter activity
zinc ion transmembrane transporter activity

Displaying 1 entry
InterPro
Zinc/iron permease

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0081141	agammaglobulinemia 9	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	14977		MGI:95909	MOUSE19854
Danio rerio	30094		ZFIN:ZDB-GENE-991110-20	DANRE15980
Drosophila melanogaster	48805		FB:FBgn0002022
Caenorhabditis elegans	181640		WB:WBGene00006494
Rattus norvegicus	294281		RGD:1593280
Pan troglodytes	462603	9598_0:001c16		PANTR37885
Canis lupus familiaris	481736			CANLF02621
Bos taurus	540716			BOVIN18268
Saccharomyces cerevisiae S288C	854789		SGD:S000001285
Monodelphis domestica	100025217			MONDO12853

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OrthoDB (Group)

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Acknowledgements