EPM2A glucan phosphatase, laforin

Summary
Gene Symbol
  • EPM2A
Aliases
  • LD
  • LDE
Organism
Homo sapiens (human)
External Links
NCBI Gene
7957
HGNC
3413
PubChem
7957
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Alternative initiation
  • Alternative splicing
  • Autophagy
  • Cell membrane
  • Cytoplasm
  • Disease variant
  • Endoplasmic reticulum
  • Epilepsy
  • Glycogen metabolism
  • Glycogen storage disease
  • Neurodegeneration
  • Nucleus
  • Phosphoprotein
  • Protein phosphatase
  • Reference proteome
  • Ubl conjugation
Proteins
Displaying 1 entry
UniProt Protein Name
O95278
  • Glucan phosphatase
  • Glycogen phosphatase
  • Lafora PTPase
Gene Ontology (GO)
GO Hierarchy
Disease
Disease Ontology
Displaying entries 51 - 60 of 77 in total
DO ID Disease Name Source
DOID:2749 glycogen storage disease Ia
DOID:2848 obsolete melancholia
DOID:2862 glucosephosphate dehydrogenase deficiency
DOID:2871 endometrial carcinoma
DOID:308 early myoclonic encephalopathy
DOID:310 MERRF syndrome
DOID:3159 photosensitivity disease
DOID:3234 central nervous system lymphoma
DOID:331 central nervous system disease
DOID:3329 benign epilepsy with centrotemporal spikes
The Human Phenotype Ontology
Displaying entries 21 - 30 of 39 in total
HPO ID HPO Term
HP:0002123 Generalized myoclonic seizure
HP:0002133 Status epilepticus
HP:0002186 Apraxia
HP:0002315 Headache
HP:0002344 Progressive neurologic deterioration
HP:0002360 Sleep abnormality
HP:0002367 Visual hallucination
HP:0002384 Focal impaired awareness seizure
HP:0002521 Hypsarrhythmia
HP:0002540 Inability to walk
Displaying all 2 entries
Disease ID Disease Name
ORPHA:501
  • Lafora disease
OMIM:254780
  • myoclonic epilepsy of Lafora 1
Ortholog
Displaying entries 61 - 63 of 63 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
109080985 CYPCA115813
116440858 CORMO18012
115613561 STRHB13439

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024