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protein phosphatase 1 regulatory subunit 3B

Summary

Gene Symbol

PPP1R3B

Aliases

FLJ14005
GL
PP1 subunit R4
PPP1R4
hepatic glycogen-targeting subunit, G(L)

Organism

Homo sapiens (human)

External Links

NCBI Gene

79660

HGNC

14942

KEGG Gene ID

hsa:79660

PubChem

79660

Alliance of Genome Resources

HGNC:14942

Annotation

Keyword

3D-structure
Glycogen metabolism
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q86XI6	Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL Protein phosphatase 1 regulatory subunit 4 Protein phosphatase 1 subunit GL

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
regulation of glycogen biosynthetic process	IBA
glycogen metabolic process	IEA
regulation of glycogen catabolic process	IDA	22225877

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

cellular process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of carbohydrate biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of catabolic process [inference]

regulation of carbohydrate catabolic process [inference]

regulation of glycogen catabolic process

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of generation of precursor metabolites and energy [inference]

regulation of glycogen metabolic process [inference]

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of polysaccharide metabolic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of glycogen metabolic process [inference]

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of polysaccharide metabolic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of glycogen metabolic process [inference]

regulation of carbohydrate biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of carbohydrate catabolic process [inference]

regulation of glycogen catabolic process

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of glycogen biosynthetic process

regulation of generation of precursor metabolites and energy [inference]

regulation of glycogen metabolic process [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
glycogen granule	IEA
protein phosphatase type 1 complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

phosphatase complex [inference]

protein serine/threonine phosphatase complex [inference]

protein phosphatase type 1 complex

cellular anatomical entity [inference]

glycogen granule

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein phosphatase regulator activity	IEA
protein phosphatase 1 binding	IBA
protein binding	IPI	15231748 32296183
glycogen binding	IBA
[phosphorylase] phosphatase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity [inference]

[phosphorylase] phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

[phosphorylase] phosphatase activity

binding [inference]

protein binding

enzyme binding [inference]

phosphatase binding [inference]

protein phosphatase binding [inference]

protein phosphatase 1 binding

carbohydrate binding [inference]

polysaccharide binding [inference]

glycogen binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

phosphatase regulator activity [inference]

protein phosphatase regulator activity

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000173281

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K07189

Name

protein phosphatase 1 regulatory subunit 3A/B/C/D/E

References

Disease

Disease Ontology

Displaying entries **1 - 10** of 30 in total

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DO ID	Disease Name	Source
DOID:0050524	maturity-onset diabetes of the young	DisGeNET
DOID:11934	head and neck cancer	DisGeNET
DOID:12139	dysthymic disorder	DisGeNET
DOID:1470	major depressive disorder	DisGeNET DisGeNET
DOID:1574	alcohol use disorder	Alliance of Genome Resources
DOID:1595	melancholic depression	DisGeNET
DOID:1596	depressive disorder	DisGeNET DisGeNET
DOID:1612	breast cancer	DisGeNET DisGeNET
DOID:162	cancer	DisGeNET DisGeNET DisGeNET
DOID:1909	melanoma	DisGeNET

Ortholog

Displaying entries **1 - 10** of 92 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	181788	WB:WBGene00019211
Drosophila melanogaster	39588	FB:FBgn0036428
Petromyzon marinus	116940661		PETMA02854
Callorhinchus milii	103182121		CALMI24355
Latimeria chalumnae	102362555		LATCH03580
Danio rerio	327285	ZFIN:ZDB-GENE-030131-5496	DANRE21260
Astyanax mexicanus	103028921		ASTMX17950
Ictalurus punctatus	108279331		ICTPU11897
Electrophorus electricus	113589042		ELEEL42631
Salmo salar	106563715		SALSA71397

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External Links

Annotation

KEGG BRITE Database

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Acknowledgements