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Guidelines

MIRAGE

STEAP4 metalloreductase

Summary

Gene Symbol

STEAP4

Organism

Homo sapiens (human)

External Links

NCBI Gene

79689

PubChem

79689

Alliance of Genome Resources

HGNC:21923

JoGo

STEAP4

TogoVar

STEAP4

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Copper
Electron transport
Endosome
FAD
Glycoprotein
Golgi apparatus
Heme
Iron transport
NADP
Oxidoreductase
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q687X5	Six-transmembrane epithelial antigen of prostate 4 SixTransMembrane protein of prostate 2 Tumor necrosis factor, alpha-induced protein 9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
copper ion import	IBA
iron import into cell	IEA
fat cell differentiation	ISS
protein homotrimerization	IDA	30337524
iron ion import across cell outer membrane

GO Hierarchy

biological process

cellular process [inference]

cellular developmental process [inference]

cell differentiation [inference]

fat cell differentiation

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport [inference]

iron ion import across cell outer membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

iron ion transmembrane transport [inference]

iron ion import across cell outer membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotrimerization

protein trimerization [inference]

protein homotrimerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotrimerization

protein trimerization [inference]

protein homotrimerization

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

fat cell differentiation

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis [inference]

iron import into cell

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis [inference]

iron import into cell

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis [inference]

iron import into cell

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis [inference]

iron import into cell

inorganic ion homeostasis [inference]

intracellular iron ion homeostasis [inference]

iron import into cell

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

copper ion transport [inference]

copper ion import

iron ion transport [inference]

iron import into cell

iron ion transmembrane transport [inference]

iron ion import across cell outer membrane

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport [inference]

iron ion import across cell outer membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport [inference]

iron ion import across cell outer membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

iron ion transmembrane transport [inference]

iron ion import across cell outer membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

iron ion transmembrane transport [inference]

iron ion import across cell outer membrane

establishment of localization in cell [inference]

iron import into cell

Displaying entries **1 - 5** of 10 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
Golgi membrane	IEA
nucleoplasm	IDA
endosome	IBA
plasma membrane	ISS
plasma membrane	IDA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

nucleoplasm

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

early endosome membrane

bounding membrane of organelle [inference]

Golgi membrane

endosome membrane

early endosome membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
cupric reductase activity	IBA
electron transfer activity	IDA	30337524
heme binding	IDA	30337524
metal ion binding	IEA
ferric-chelate reductase (NADPH) activity	IDA	30337524

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

electron transfer activity

oxidoreductase activity, acting on metal ions [inference]

ferric-chelate reductase activity [inference]

ferric-chelate reductase (NADPH) activity

oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor [inference]

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding [inference]

FAD binding

ion binding [inference]

anion binding [inference]

flavin adenine dinucleotide binding [inference]

FAD binding

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding [inference]

FAD binding

Gene Ontology information from NCBI Gene and UniProt.

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026