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2-oxoglutarate and iron dependent oxygenase domain containing 3

Summary

Gene Symbol

OGFOD3

Organism

Homo sapiens (human)

External Links

NCBI Gene

79701

PubChem

79701

Alliance of Genome Resources

HGNC:26174

Annotation

Keyword

Alternative splicing
Dioxygenase
Glycoprotein
Iron
Metal-binding
Reference proteome
Signal-anchor
Transmembrane helix
Vitamin C

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6PK18

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
membrane	HDA	19946888

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
iron ion binding	IEA
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA
L-ascorbic acid binding	IEA
dioxygenase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

binding [inference]

carbohydrate binding [inference]

monosaccharide binding [inference]

L-ascorbic acid binding

small molecule binding [inference]

vitamin binding [inference]

L-ascorbic acid binding

organic acid binding [inference]

carboxylic acid binding [inference]

L-ascorbic acid binding

monosaccharide binding [inference]

L-ascorbic acid binding

heterocyclic compound binding [inference]

L-ascorbic acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

L-ascorbic acid binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

organic cyclic compound binding [inference]

L-ascorbic acid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 6** entries
Gene Ontology
L-ascorbic acid binding
dioxygenase activity
iron ion binding
metal ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity

Displaying **all 4** entries
InterPro
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3
Oxoglutarate/iron-dependent dioxygenase
Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain
Prolyl 4-hydroxylase, alpha subunit

Ortholog

Displaying entries **1 - 10** of 61 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	66179	Xenbase:XB-GENE-6457975	MOUSE05450
Xenopus tropicalis	79701	Xenbase:XB-GENE-6457975
Rattus norvegicus	303749	Xenbase:XB-GENE-6457975	RATNO02733
Pan troglodytes	454991		PANTR15749
Xenopus tropicalis	496518	Xenbase:XB-GENE-6457975
Bos taurus	506185		BOVIN13702
Danio rerio	559344		DANRE03520
Canis lupus familiaris	608209		CANLF20598
Macaca mulatta	716172		MACMU14868
Equus caballus	100056827		HORSE03271