leucine rich repeat kinase 1

Summary
Gene Symbol
  • LRRK1
Organism
Homo sapiens (human)
NCBI Gene
79705
PubChem
79705
Alliance of Genome Resources
JoGo
LRRK1
TogoVar
LRRK1
Annotation
Keyword
  • 3D-structure
  • ANK repeat
  • ATP-binding
  • Alternative splicing
  • Cell membrane
  • Cytoplasm
  • Disease variant
  • GTP-binding
  • Leucine-rich repeat
  • Magnesium
  • Manganese
  • Metal-binding
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Repeat
  • Serine/threonine-protein kinase
  • WD repeat
Proteins
Displaying 1 entry
UniProt Protein Name
Q38SD2
Gene Ontology (GO)
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
leucine-rich repeat kinase 1
Functional Category
  • K: Transcription
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:0081111 osteosclerotic metaphyseal dysplasia

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 8, 2025