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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
tissue factor pathway inhibitor 2
Summary
- Gene Symbol
-
- TFPI2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Blood coagulation
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Reference proteome
- Repeat
- Secreted
- Serine protease inhibitor
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P48307 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of peptidase activity | ||
| cellular response to fluid shear stress | ||
| blood coagulation |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular matrix | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular matrix structural constituent | ||
| serine-type endopeptidase inhibitor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Kunitz-type serine protease inhibitor
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| peptidase inhibitor activity |
| serine-type endopeptidase inhibitor activity |
| InterPro |
|---|
| Pancreatic trypsin inhibitor Kunitz domain superfamily |
| Pancreatic trypsin inhibitor Kunitz domain |
| Proteinase inhibitor I2, Kunitz, conserved site |
Disease
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 21789 | MGI:108543 | MOUSE51017 | ||
| 35896 | FB:FBgn0033355 | |||
| 179593 | WB:WBGene00009386 | |||
| 183787 | WB:WBGene00008304 | |||
| 286926 | RGD:628629 | RATNO29651 | ||
| 326147 | FB:FBgn0051515 | |||
| 360007 | BOVIN27614 | |||
| 379525 | Xenbase:XB-GENE-6255487 | |||
| 463540 | 9598_0:00215f | PANTR40761 | ||
| 475230 | CANLF03660 |
