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EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase

Summary

Gene Symbol

eogt

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

798087

KEGG Gene ID

dre:798087

PubChem

798087

Alliance of Genome Resources

ZFIN:ZDB-GENE-120813-8

Annotation

Keyword

Glycoprotein
Glycosyltransferase
Reference proteome
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
X1WGG5	Extracellular O-linked N-acetylglucosamine transferase
A0A8M9QDI0	Extracellular O-linked N-acetylglucosamine transferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
protein O-GlcNAcylation via threonine	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

peptidyl-amino acid modification [inference]

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

peptidyl-amino acid modification [inference]

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

peptidyl-amino acid modification [inference]

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

peptidyl-amino acid modification [inference]

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

peptidyl-amino acid modification [inference]

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine [inference]

protein O-GlcNAcylation via threonine

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum lumen	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein O-acetylglucosaminyltransferase activity	IBA IEA
transferase activity	IEA
glycosyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

protein O-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

protein O-acetylglucosaminyltransferase activity

catalytic activity, acting on a protein [inference]

protein O-acetylglucosaminyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

egf domain-specific o-linked n-acetylglucosamine transferase

Functional Category

D: Cell cycle control, cell division, chromosome partitioning
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying 1 entry
Gene Ontology
transferase activity

Displaying **all 2** entries
InterPro
Glycosyltransferase 61, catalytic domain
Glycosyltransferase 61

KEGG BRITE Database

Orthology

K18134

Name

EGF domain-specific O-GlcNAc transferase [EC:2.4.1.255]

References

22158438

Rhea

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.255

PMID

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.255

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060227	Adams-Oliver syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **243** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	33424		FB:FBgn0264672
Mus musculus	101351		MGI:2141669	MOUSE48836
Caenorhabditis elegans	179990		WB:WBGene00010386
Homo sapiens	285203		HGNC:28526	HUMAN70896
Rattus norvegicus	494219		RGD:1359357	RATNO31616
Pan troglodytes	494220			PANTR31528
Canis lupus familiaris	494221			CANLF07354
Ciona intestinalis	497240			CIOIN10572
Bos taurus	508782			BOVIN17521
Macaca mulatta	696742			MACMU29625

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024