GlyCosmos Portal

Annotation

Keyword

Acyltransferase
Calcium
Cell membrane
Endoplasmic reticulum
Golgi apparatus
Lipid droplet
Metal-binding
Phospholipid biosynthesis
Reference proteome
Repeat
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8NF37	1-acylglycerol-3-phosphate O-acyltransferase 1-acylglycerophosphocholine O-acyltransferase 1-alkenylglycerophosphocholine O-acyltransferase 1-alkylglycerophosphocholine O-acetyltransferase Acetyl-CoA:lyso-platelet-activating factor acetyltransferase Acyltransferase-like 2 Phosphonoformate immuno-associated protein 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
phospholipid biosynthetic process	ISS
retina development in camera-type eye	IEA
phosphatidylcholine acyl-chain remodeling	IDA TAS	21498505
negative regulation of phosphatidylcholine biosynthetic process	IEA
positive regulation of protein catabolic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein catabolic process

phosphatidylcholine metabolic process [inference]

organonitrogen compound catabolic process [inference]

protein catabolic process

organonitrogen compound biosynthetic process [inference]

phosphatidylcholine biosynthetic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

phosphatidylcholine biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidic acid metabolic process [inference]

phosphatidic acid biosynthetic process

glycerophospholipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidic acid metabolic process [inference]

phosphatidic acid biosynthetic process

glycerophospholipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidic acid metabolic process [inference]

phosphatidic acid biosynthetic process

glycerophospholipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidic acid metabolic process [inference]

phosphatidic acid biosynthetic process

glycerophospholipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidic acid metabolic process [inference]

phosphatidic acid biosynthetic process

glycerophospholipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidic acid metabolic process [inference]

phosphatidic acid biosynthetic process

glycerophospholipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

protein metabolic process [inference]

protein catabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidic acid metabolic process [inference]

phosphatidic acid biosynthetic process

glycerophospholipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidic acid metabolic process [inference]

phosphatidic acid biosynthetic process

glycerophospholipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidic acid metabolic process [inference]

phosphatidic acid biosynthetic process

glycerophospholipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

protein metabolic process [inference]

protein catabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein catabolic process

phosphatidylcholine metabolic process [inference]

organonitrogen compound catabolic process [inference]

protein catabolic process

organonitrogen compound biosynthetic process [inference]

phosphatidylcholine biosynthetic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

phosphatidylcholine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidic acid metabolic process [inference]

phosphatidic acid biosynthetic process

glycerophospholipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidic acid metabolic process [inference]

phosphatidic acid biosynthetic process

glycerophospholipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidic acid metabolic process [inference]

phosphatidic acid biosynthetic process

glycerophospholipid biosynthetic process [inference]

phospholipid biosynthetic process

glycerophospholipid biosynthetic process [inference]

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol acyl-chain remodeling

phosphatidic acid metabolic process [inference]

phosphatidic acid biosynthetic process

glycerophospholipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

surfactant homeostasis

developmental process [inference]

anatomical structure development [inference]

retina development in camera-type eye

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

surfactant homeostasis

chemical homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

surfactant homeostasis

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of cellular biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phosphatidylcholine biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of lipid biosynthetic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phospholipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phosphatidylcholine biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of cellular biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phosphatidylcholine biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phosphate metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phospholipid metabolic process [inference]

regulation of phospholipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phosphatidylcholine biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phosphatidylcholine biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phosphatidylcholine biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

negative regulation of lipid metabolic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of lipid biosynthetic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phospholipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phosphatidylcholine biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phospholipid metabolic process [inference]

regulation of phospholipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phosphatidylcholine biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phosphatidylcholine biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of cellular biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phosphatidylcholine biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phosphate metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phospholipid metabolic process [inference]

regulation of phospholipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phosphatidylcholine biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

regulation of phosphatidylcholine biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of phosphatidylcholine metabolic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of phosphatidylcholine biosynthetic process

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GO Term	Evidence Code	PMID
endoplasmic reticulum	IBA IDA ISS	21498505
azurophil granule membrane
lipid droplet	IDA	21498505
endoplasmic reticulum membrane
plasma membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane [inference]

azurophil granule membrane

bounding membrane of organelle [inference]

Golgi membrane

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane [inference]

azurophil granule membrane

secretory granule membrane [inference]

azurophil granule membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

lipid droplet

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

lipid droplet

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GO Term	Evidence Code	PMID
1-alkylglycerophosphocholine O-acetyltransferase activity	ISS
lysophosphatidic acid acyltransferase activity	IBA
1-alkylglycerophosphocholine O-acyltransferase activity	IEA
1-acylglycerophosphocholine O-acyltransferase activity	IDA ISS	18156367 21498505
1-acylglycerol-3-phosphate O-acyltransferase activity	ISS TAS

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

O-acyltransferase activity [inference]

acylglycerol O-acyltransferase activity [inference]

1-acylglycerol-3-phosphate O-acyltransferase activity

O-acetyltransferase activity [inference]

1-alkylglycerophosphocholine O-acetyltransferase activity

acetyltransferase activity [inference]

O-acetyltransferase activity [inference]

1-alkylglycerophosphocholine O-acetyltransferase activity

lysophospholipid acyltransferase activity [inference]

lysophosphatidic acid acyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000153395

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K13510

Name

lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]

References

Rhea

RHEA:19709

a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA

CoA + a 1,2-diacyl-sn-glycero-3-phosphate

Enzyme

2.3.1.51

PMID

RHEA:10344

an acyl-CoA + 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine

CoA + 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine

Enzyme

2.3.1.25

PMID

RHEA:12937

a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA

CoA + a 1,2-diacyl-sn-glycero-3-phosphocholine

Enzyme

2.3.1.23

PMID

RHEA:18461

1-O-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA

a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA

Enzyme

2.3.1.67

PMID

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:0050387	nonpapillary renal cell carcinoma	DisGeNET
DOID:0050572	cone-rod dystrophy	DisGeNET
DOID:10283	prostate cancer	DisGeNET DisGeNET
DOID:10286	prostate carcinoma	DisGeNET DisGeNET
DOID:10354	breast fibrocystic disease	DisGeNET
DOID:10584	retinitis pigmentosa	DisGeNET
DOID:10923	sickle cell anemia	DisGeNET
DOID:11105	fundus albipunctatus	DisGeNET
DOID:11394	adult respiratory distress syndrome	DisGeNET DisGeNET
DOID:12716	newborn respiratory distress syndrome	DisGeNET DisGeNET

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP005910
Gene Name: lysophosphatidylcholine acyltransferase 1

Ortholog

Displaying entries **1 - 10** of 85 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	31899	FB:FBgn0052699
Callorhinchus milii	103184820		CALMI03548
Danio rerio	555969	ZFIN:ZDB-GENE-060503-915	DANRE16056
Astyanax mexicanus	103025479		ASTMX00920
Astyanax mexicanus	103025629		ASTMX09084
Ictalurus punctatus	108272334		ICTPU03985
Esox lucius	105016610		ESOLU48253
Salmo trutta	115175643		SALTR04657
Gadus morhua	115536176		GADMO34378
Gadus morhua	115554128		GADMO04549

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements