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MIRAGE
platelet derived growth factor D
Summary
- Gene Symbol
-
- PDGFD
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Cleavage on pair of basic residues
- Developmental protein
- Disulfide bond
- Glycoprotein
- Growth factor
- Mitogen
- Proto-oncogene
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9GZP0 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of cell population proliferation | ||
| positive regulation of cell migration | ||
| cellular response to platelet-derived growth factor stimulus | ||
| platelet-derived growth factor receptor signaling pathway | ||
| positive regulation of fibroblast proliferation |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of signaling [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cell population proliferation [inference]
positive regulation of cellular process [inference]
regulation of cell motility [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi membrane | ||
| extracellular region | ||
| extracellular space | ||
| endoplasmic reticulum lumen |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| platelet-derived growth factor receptor binding | ||
| growth factor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- platelet-derived growth factor C
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| CUB domain |
| Cystine-knot cytokine |
| PDGF/VEGF domain |
| Spermadhesin, CUB domain superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11132 | prostatic hypertrophy |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 66018 | Xenbase:XB-GENE-985911 | RATNO40335 | |
| 71785 | Xenbase:XB-GENE-985911 | MOUSE64495 | |
| 80310 | Xenbase:XB-GENE-985911 | ||
| 466765 | PANTR04196 | ||
| 479460 | CANLF15341 | ||
| 525931 | BOVIN06317 | ||
| 704310 | MACMU11131 | ||
| 100011261 | MONDO20761 | ||
| 100078558 | ORNAN13683 | ||
| 100172718 | PONAB04381 |
