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solute carrier family 26, member 5

Summary

Gene Symbol

Slc26a5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

80979

PubChem

80979

Alliance of Genome Resources

MGI:1933154

Annotation

Keyword

Cell membrane
Cell shape
Glycoprotein
Hearing
Motor protein
Reference proteome
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q99NH7	Solute carrier family 26 member 5
Q32MT7	Solute carrier family 26 member 5
Q32MT6	Solute carrier family 26 member 5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	PMID
sensory perception of sound	IEA ISO
positive regulation of cell motility	IEA ISO
response to ischemia	IEA
negative regulation of ion transmembrane transport	IEA ISO
regulation of cell shape	IEA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

fructose transmembrane transport

monoatomic ion transmembrane transport

monoatomic anion transmembrane transport

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

regulation of cellular component size [inference]

regulation of cell size [inference]

positive regulation of cell size

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

developmental process [inference]

anatomical structure development [inference]

cochlea development

response to stimulus [inference]

response to stress [inference]

response to ischemia

response to external stimulus [inference]

response to mechanical stimulus [inference]

response to auditory stimulus

response to abiotic stimulus [inference]

response to mechanical stimulus [inference]

response to auditory stimulus

response to endogenous stimulus [inference]

response to hormone [inference]

response to thyroid hormone

response to chemical [inference]

response to xenobiotic stimulus

response to organic substance [inference]

response to hormone [inference]

response to thyroid hormone

response to organic cyclic compound [inference]

response to salicylic acid

response to inorganic substance [inference]

response to metal ion [inference]

response to potassium ion

response to oxygen-containing compound [inference]

response to salt

response to potassium ion

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic anion transport [inference]

chloride transport

chloride transmembrane transport

monoatomic anion transmembrane transport

chloride transmembrane transport

monoatomic ion transmembrane transport

monoatomic anion transmembrane transport

chloride transmembrane transport

inorganic anion transport [inference]

chloride transport

chloride transmembrane transport

sulfate transport [inference]

sulfate transmembrane transport

inorganic anion transmembrane transport [inference]

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

fructose transmembrane transport

monoatomic ion transmembrane transport

monoatomic anion transmembrane transport

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

organic substance transport [inference]

carbohydrate transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

fructose transmembrane transport

organic anion transport [inference]

bicarbonate transport

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

oxalate transport

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

oxalate transport

one-carbon compound transport [inference]

bicarbonate transport

nitrogen compound transport [inference]

sulfate transport [inference]

sulfate transmembrane transport

oxalate transport

sulfur compound transport [inference]

sulfate transport [inference]

sulfate transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport

regulation of monoatomic ion transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility

regulation of cell motility [inference]

positive regulation of cell motility

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility

positive regulation of cellular process [inference]

positive regulation of cell motility

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport

positive regulation of cellular process [inference]

positive regulation of cell motility

negative regulation of cellular process [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport

regulation of cell motility [inference]

positive regulation of cell motility

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of cell size [inference]

positive regulation of cell size

Displaying **all 4** entries
GO Term	Evidence Code	PMID
lateral plasma membrane	IDA ISO	18796539
plasma membrane	IBA IDA TAS	24303013
lateral wall of outer hair cell	IDA	25748314
basolateral plasma membrane	IDA ISO	12584604

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

basolateral plasma membrane

lateral plasma membrane

lateral part of cell [inference]

lateral wall of outer hair cell

Displaying entries **6 - 10** of 10 in total

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GO Term	Evidence Code	PMID
chloride transmembrane transporter activity	IBA
identical protein binding	ISO
bicarbonate transmembrane transporter activity	IBA
protein homodimerization activity	ISO ISS
chloride:bicarbonate antiporter activity	ISO ISS

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

dicarboxylic acid transmembrane transporter activity [inference]

oxalate transmembrane transporter activity

organic anion transmembrane transporter activity [inference]

bicarbonate transmembrane transporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

carboxylic acid transmembrane transporter activity [inference]

dicarboxylic acid transmembrane transporter activity [inference]

oxalate transmembrane transporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic anion transmembrane transporter activity [inference]

chloride transmembrane transporter activity

chloride:bicarbonate antiporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

active monoatomic ion transmembrane transporter activity [inference]

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic anion transmembrane transporter activity [inference]

solute:inorganic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

chloride transmembrane transporter activity

chloride:bicarbonate antiporter activity

sulfate transmembrane transporter activity

secondary active sulfate transmembrane transporter activity

bicarbonate transmembrane transporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

secondary active sulfate transmembrane transporter activity

antiporter activity [inference]

solute:inorganic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

active monoatomic ion transmembrane transporter activity [inference]

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

sulfur compound transmembrane transporter activity [inference]

sulfate transmembrane transporter activity

secondary active sulfate transmembrane transporter activity

salt transmembrane transporter activity [inference]

bicarbonate transmembrane transporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

chloride transmembrane transporter activity

chloride:bicarbonate antiporter activity

sulfate transmembrane transporter activity

secondary active sulfate transmembrane transporter activity

oxalate transmembrane transporter activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

spectrin binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

protein-containing complex binding [inference]

spectrin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Glycosyl hydrolase family 38, C-terminal

Functional Category

G: Carbohydrate transport and metabolism
K: Transcription
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
bicarbonate transmembrane transporter activity
inorganic anion transmembrane transport
inorganic anion transport
monoatomic anion transmembrane transporter activity
oxalate transmembrane transporter activity
secondary active sulfate transmembrane transporter activity
sensory perception of sound
sulfate transmembrane transport
sulfate transmembrane transporter activity

Displaying **all 5** entries
InterPro
SLC26A/SulP transporter domain
SLC26A/SulP transporter
STAS domain superfamily
STAS domain
Sulphate anion transporter, conserved site

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0110513	autosomal recessive nonsyndromic deafness 61	Alliance of Genome Resources
DOID:1459	hypothyroidism	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **125** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	39996		FB:FBgn0036770
Rattus norvegicus	83819	10116_1:0018a9	RGD:69334	RATNO29592
Caenorhabditis elegans	179357		WB:WBGene00013963
Caenorhabditis elegans	179626		WB:WBGene00010788
Caenorhabditis elegans	183842		WB:WBGene00016945
Caenorhabditis elegans	187335		WB:WBGene00010789
Danio rerio	322846		ZFIN:ZDB-GENE-030131-1566	DANRE33215
Homo sapiens	375611		HGNC:9359	HUMAN90631
Ciona intestinalis	445732			CIOIN11675
Canis lupus familiaris	483274			CANLF05552