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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
integrin subunit alpha 7
Summary
- Gene Symbol
-
- Itga7
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- ADP-ribosylation
- Alternative splicing
- Calcium
- Cell adhesion
- Cell shape
- Cleavage on pair of basic residues
- Disulfide bond
- Glycoprotein
- Integrin
- Metal-binding
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of cell shape | ||
| skeletal muscle tissue development | ||
| cell migration | ||
| heterotypic cell-cell adhesion | ||
| blood vessel morphogenesis |
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| sarcolemma | ||
| muscle tendon junction | ||
| neuromuscular junction | ||
| integrin complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| integrin binding | ||
| protein-containing complex binding | ||
| metal ion binding | ||
| cell adhesion molecule binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- integrin alpha-7
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- M: Cell wall/membrane/envelope biogenesis
| Gene Ontology |
|---|
| cell adhesion mediated by integrin |
| cell-matrix adhesion |
| integrin binding |
| integrin-mediated signaling pathway |
| leukocyte migration |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050700 | cardiomyopathy | |
| DOID:0080000 | muscular disease | |
| DOID:0110639 | congenital muscular dystrophy due to integrin alpha-7 deficiency | |
| DOID:11723 | Duchenne muscular dystrophy | |
| DOID:162 | cancer | |
| DOID:1826 | epilepsy | |
| DOID:2349 | arteriosclerosis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 114681739 | 10041_0:003aeb | |||
| 115150057 | SALTR32667 | |||
| 115207310 | SALTR36704 | |||
| 115388661 | SALFA37117 | |||
| 115557472 | GADMO11189 | |||
| 115583764 | SPAAU42358 | |||
| 116075887 | 35658_0:003f17 | |||
| 116906626 | 10117_0:0005f3 | |||
| 117028729 | RHIFE09395 | |||
| 117696405 | 61156_0:004a33 |
