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solute carrier family 7 member 5

Summary

Gene Symbol

SLC7A5

Organism

Homo sapiens (human)

External Links

NCBI Gene

8140

PubChem

8140

Alliance of Genome Resources

HGNC:11063

Annotation

Keyword

3D-structure
Amino-acid transport
Cell membrane
Direct protein sequencing
Disulfide bond
Isopeptide bond
Lysosome
Phosphoprotein
Reference proteome
Transmembrane helix
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q01650	4F2 light chain CD98 light chain Integral membrane protein E16 L-type amino acid transporter 1 Solute carrier family 7 member 5 y+ system cationic amino acid transporter

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 39 in total

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GO Term	Evidence Code	PMID
positive regulation of cytokine production involved in immune response	TAS	24038088
amino acid transmembrane transport	IBA
negative regulation of autophagy	IEA
negative regulation of gene expression	IMP	24038088
response to muscle activity	IEA

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to chemical stimulus [inference]

cellular response to acid chemical [inference]

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to organonitrogen compound [inference]

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

transmembrane transport [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport

amino acid import across plasma membrane

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier

developmental process [inference]

anatomical structure development [inference]

regeneration [inference]

animal organ regeneration [inference]

liver regeneration

animal organ development [inference]

animal organ regeneration [inference]

liver regeneration

gland development [inference]

liver development [inference]

liver regeneration

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

response to hyperoxia

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

cellular response to external stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to abiotic stimulus [inference]

response to oxygen levels [inference]

response to increased oxygen levels [inference]

response to hyperoxia

response to endogenous stimulus [inference]

cellular response to endogenous stimulus [inference]

cellular response to organonitrogen compound [inference]

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

response to activity [inference]

response to muscle activity

response to chemical [inference]

response to acid chemical [inference]

response to amino acid [inference]

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

response to L-arginine [inference]

cellular response to L-arginine

cellular response to acid chemical [inference]

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to organonitrogen compound [inference]

response to amino acid [inference]

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

response to L-arginine [inference]

cellular response to L-arginine

cellular response to organonitrogen compound [inference]

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

response to lipid [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to organonitrogen compound [inference]

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

cellular response to chemical stimulus [inference]

cellular response to acid chemical [inference]

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to organonitrogen compound [inference]

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to amino acid [inference]

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

response to L-arginine [inference]

cellular response to L-arginine

cellular response to organonitrogen compound [inference]

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

response to oxygen-containing compound [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

response to amino acid [inference]

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

response to L-arginine [inference]

cellular response to L-arginine

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to chemical stimulus [inference]

cellular response to acid chemical [inference]

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to organonitrogen compound [inference]

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to amino acid stimulus [inference]

cellular response to L-arginine

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

localization [inference]

establishment of localization [inference]

transport [inference]

hormone transport [inference]

thyroid hormone transport

vascular transport [inference]

transport across blood-brain barrier

xenobiotic transport

transmembrane transport [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport

amino acid import across plasma membrane

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

sulfur amino acid transport [inference]

methionine transport

amino acid transmembrane transport

amino acid import across plasma membrane

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

aromatic amino acid transport [inference]

tryptophan transport

L-tryptophan transmembrane transport

basic amino acid transport [inference]

histidine transport [inference]

L-histidine transport

branched-chain amino acid transport [inference]

isoleucine transport

leucine transport

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

valine transport

neutral amino acid transport

isoleucine transport

leucine transport

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-amino acid transport [inference]

L-histidine transport

L-alpha-amino acid transmembrane transport [inference]

phenylalanine transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport

amino acid import across plasma membrane

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

organic acid transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

sulfur amino acid transport [inference]

methionine transport

amino acid transmembrane transport

amino acid import across plasma membrane

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

aromatic amino acid transport [inference]

tryptophan transport

L-tryptophan transmembrane transport

basic amino acid transport [inference]

histidine transport [inference]

L-histidine transport

branched-chain amino acid transport [inference]

isoleucine transport

leucine transport

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

valine transport

neutral amino acid transport

isoleucine transport

leucine transport

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-amino acid transport [inference]

L-histidine transport

L-alpha-amino acid transmembrane transport [inference]

phenylalanine transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport

amino acid import across plasma membrane

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport

amino acid import across plasma membrane

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

nitrogen compound transport [inference]

amino acid transport [inference]

sulfur amino acid transport [inference]

methionine transport

amino acid transmembrane transport

amino acid import across plasma membrane

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

aromatic amino acid transport [inference]

tryptophan transport

L-tryptophan transmembrane transport

basic amino acid transport [inference]

histidine transport [inference]

L-histidine transport

branched-chain amino acid transport [inference]

isoleucine transport

leucine transport

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

valine transport

neutral amino acid transport

isoleucine transport

leucine transport

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

L-amino acid transport [inference]

L-histidine transport

L-alpha-amino acid transmembrane transport [inference]

phenylalanine transport

sulfur compound transport [inference]

sulfur amino acid transport [inference]

methionine transport

import into cell [inference]

amino acid import across plasma membrane

leucine import across plasma membrane [inference]

L-leucine import across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-17 production [inference]

positive regulation of interleukin-17 production

regulation of interleukin-4 production [inference]

positive regulation of interleukin-4 production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

negative regulation of autophagy

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-17 production [inference]

positive regulation of interleukin-17 production

regulation of interleukin-4 production [inference]

positive regulation of interleukin-4 production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

negative regulation of autophagy

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-17 production [inference]

positive regulation of interleukin-17 production

regulation of interleukin-4 production [inference]

positive regulation of interleukin-4 production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of localization [inference]

regulation of transport [inference]

regulation of organic acid transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of leucine import across plasma membrane

regulation of amino acid transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of leucine import across plasma membrane

regulation of amino acid transmembrane transport [inference]

regulation of amino acid import across plasma membrane [inference]

regulation of leucine import across plasma membrane [inference]

positive regulation of leucine import across plasma membrane

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of leucine import across plasma membrane

regulation of amino acid transmembrane transport [inference]

regulation of amino acid import across plasma membrane [inference]

regulation of leucine import across plasma membrane [inference]

positive regulation of leucine import across plasma membrane

positive regulation of transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of leucine import across plasma membrane

positive regulation of transmembrane transport [inference]

positive regulation of leucine import across plasma membrane

positive regulation of amine transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of leucine import across plasma membrane

regulation of amine transport [inference]

positive regulation of amine transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of leucine import across plasma membrane

regulation of amino acid transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of leucine import across plasma membrane

regulation of amino acid transmembrane transport [inference]

regulation of amino acid import across plasma membrane [inference]

regulation of leucine import across plasma membrane [inference]

positive regulation of leucine import across plasma membrane

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of glial cell proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of transmembrane transport [inference]

positive regulation of leucine import across plasma membrane

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of leucine import across plasma membrane

positive regulation of transmembrane transport [inference]

positive regulation of leucine import across plasma membrane

positive regulation of amine transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of leucine import across plasma membrane

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of muscle cell apoptotic process [inference]

negative regulation of smooth muscle cell apoptotic process [inference]

negative regulation of vascular associated smooth muscle cell apoptotic process

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-17 production [inference]

positive regulation of interleukin-17 production

regulation of interleukin-4 production [inference]

positive regulation of interleukin-4 production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

negative regulation of autophagy

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of leucine import across plasma membrane

regulation of amino acid transmembrane transport [inference]

regulation of amino acid import across plasma membrane [inference]

regulation of leucine import across plasma membrane [inference]

positive regulation of leucine import across plasma membrane

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of glial cell proliferation

regulation of glial cell proliferation [inference]

positive regulation of glial cell proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

regulation of muscle cell apoptotic process [inference]

negative regulation of muscle cell apoptotic process [inference]

negative regulation of smooth muscle cell apoptotic process [inference]

negative regulation of vascular associated smooth muscle cell apoptotic process

regulation of smooth muscle cell apoptotic process [inference]

negative regulation of smooth muscle cell apoptotic process [inference]

negative regulation of vascular associated smooth muscle cell apoptotic process

regulation of vascular associated smooth muscle cell apoptotic process [inference]

negative regulation of vascular associated smooth muscle cell apoptotic process

negative regulation of apoptotic process [inference]

negative regulation of muscle cell apoptotic process [inference]

negative regulation of smooth muscle cell apoptotic process [inference]

negative regulation of vascular associated smooth muscle cell apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of muscle cell apoptotic process [inference]

negative regulation of smooth muscle cell apoptotic process [inference]

negative regulation of vascular associated smooth muscle cell apoptotic process

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of glial cell proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of transmembrane transport [inference]

positive regulation of leucine import across plasma membrane

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular catabolic process [inference]

negative regulation of autophagy

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of muscle cell apoptotic process [inference]

negative regulation of smooth muscle cell apoptotic process [inference]

negative regulation of vascular associated smooth muscle cell apoptotic process

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-17 production [inference]

positive regulation of interleukin-17 production

regulation of interleukin-4 production [inference]

positive regulation of interleukin-4 production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone transport [inference]

thyroid hormone transport

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GO Term	Evidence Code	PMID
lysosomal membrane	IEA
cytosol	IDA
plasma membrane	TAS
plasma membrane	IDA	11557028 12225859 16496379 19075510 23137377 25998567 28112518 9751058
basal plasma membrane	ISS	18619525

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

amino acid transport complex

cellular anatomical entity [inference]

cytosol

membrane

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

plasma membrane region [inference]

cell projection membrane [inference]

microvillus membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

side of membrane [inference]

external side of plasma membrane [inference]

external side of apical plasma membrane

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GO Term	Evidence Code	PMID
protein binding	IPI	25998567 30867591 30996345 31160781 35271311
amino acid transmembrane transporter activity	ISS
amino acid transmembrane transporter activity	IDA	26305885
amino acid transmembrane transporter activity	IMP	23567998 30374619
aromatic amino acid transmembrane transporter activity	IGI	15589117

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity

aromatic amino acid transmembrane transporter activity

L-tryptophan transmembrane transporter activity

neutral L-amino acid transmembrane transporter activity

L-leucine transmembrane transporter activity

L-amino acid transmembrane transporter activity

branched-chain amino acid transmembrane transporter activity [inference]

L-leucine transmembrane transporter activity

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity

aromatic amino acid transmembrane transporter activity

L-tryptophan transmembrane transporter activity

neutral L-amino acid transmembrane transporter activity

L-leucine transmembrane transporter activity

L-amino acid transmembrane transporter activity

branched-chain amino acid transmembrane transporter activity [inference]

L-leucine transmembrane transporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

binding [inference]

antigen binding [inference]

peptide antigen binding

protein binding

amide binding [inference]

peptide binding [inference]

peptide antigen binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

transporter

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:219	colon cancer	Alliance of Genome Resources
DOID:3907	lung squamous cell carcinoma	Alliance of Genome Resources
DOID:4947	cholangiocarcinoma	Alliance of Genome Resources
DOID:684	hepatocellular carcinoma	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	8140	Xenbase:XB-GENE-480035
Saccharomyces cerevisiae S288C	9056	SGD:S000003287
Mus musculus	20539	Xenbase:XB-GENE-480035	MOUSE58939
Saccharomyces cerevisiae S288C	20540	SGD:S000001028
Saccharomyces cerevisiae S288C	23657	SGD:S000003287
Rattus norvegicus	50719		RATNO15145
Saccharomyces cerevisiae S288C	83509	SGD:S000001028
Saccharomyces cerevisiae S288C	188421	SGD:S000001028
Bos taurus	282369		BOVIN10284
Pan troglodytes	454300		PANTR13043

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements