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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
calcium/calmodulin dependent protein kinase II delta
Summary
- Gene Symbol
-
- CAMK2D
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Alternative splicing
- Calmodulin-binding
- Cell membrane
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Sarcoplasmic reticulum
- Serine/threonine-protein kinase
- Proteins
| UniProt | Protein Name |
|---|---|
| E9PF82 |
|
| A0A994J5B0 |
|
| Q13557 |
|
| A0A8V8TPY4 |
|
| A0A8V8TN60 |
|
| E9PBG7 |
|
| A0A8V8TN88 |
|
| D6R938 |
|
| A0A8V8TN65 |
|
| A0A8V8TPJ8 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of sodium ion transmembrane transport | ||
| regulation of cell communication by electrical coupling | ||
| regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | ||
| regulation of heart contraction | ||
| regulation of protein localization to plasma membrane |
GO Hierarchy
- regulation of membrane depolarization
biological process
metabolic process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of transmembrane transport [inference]
regulation of transmembrane transporter activity [inference]
regulation of monoatomic ion transmembrane transport [inference]
regulation of monoatomic ion transport [inference]
regulation of metal ion transport [inference]
regulation of monoatomic ion transmembrane transport [inference]
regulation of sequestering of calcium ion [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
regulation of transmembrane transport [inference]
regulation of transmembrane transporter activity [inference]
regulation of monoatomic ion transmembrane transport [inference]
regulation of programmed cell death [inference]
regulation of sequestering of calcium ion [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| sarcoplasmic reticulum membrane | ||
| membrane | ||
| sarcolemma | ||
| postsynaptic density | ||
| endocytic vesicle membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| protein serine kinase activity | ||
| calmodulin binding | ||
| protein serine/threonine kinase activity | ||
| identical protein binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- calcium/calmodulin-dependent protein kinase type II
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ATP binding |
| calmodulin binding |
| InterPro |
|---|
| Protein kinase domain |
| Protein kinase-like domain superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10273 | heart conduction disease | |
| DOID:1591 | renovascular hypertension | |
| DOID:1826 | epilepsy | |
| DOID:5844 | myocardial infarction |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 24246 | RGD:2263 | RATNO25344 | ||
| 43828 | FB:FBgn0264607 | |||
| 108058 | MGI:1341265 | MOUSE37223 | ||
| 177921 | WB:WBGene00006779 | |||
| 398376 | Xenbase:XB-GENE-17333849 | |||
| 399160 | Xenbase:XB-GENE-868304 | |||
| 436815 | ZFIN:ZDB-GENE-040718-277 | |||
| 445208 | ZFIN:ZDB-GENE-040801-121 | |||
| 461445 | 9598_0:0016b6 | |||
| 610764 | CANLF13174 |
