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Inositol phosphorylceramide synthase 2

Summary

Gene Symbol

AtIPCS2

Organism

Arabidopsis thaliana (thale cress)

External Links

NCBI Gene: 818371
PubChem: 818371

Annotation

Keyword

Golgi apparatus
Lipid biosynthesis
Plant defense
Reference proteome
Sphingolipid metabolism
Transferase
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A178VV03
Q9SH93	Inositol-phosphorylceramide synthase 2 Protein ENHANCING RPW8-MEDIATED HR-LIKE CELL DEATH 1 Sphingolipid synthase 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
defense response	IEP	31568832
ceramide biosynthetic process
sphingolipid biosynthetic process	IDA	20309609

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

amide metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

amide biosynthetic process [inference]

ceramide biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process

ceramide biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process

ceramide biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

response to stimulus [inference]

response to stress [inference]

defense response

Displaying **all 3** entries
GO Term	Evidence Code	PMID
trans-Golgi network	IDA	19001565
plasma membrane	ISM
membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

plasma membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

Displaying **all 4** entries
GO Term	Evidence Code	PMID
ceramide cholinephosphotransferase activity
sphingomyelin synthase activity
inositol phosphoceramide synthase activity	IDA IMP	20309609
phosphotransferase activity, for other substituted phosphate groups	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

inositol phosphoceramide synthase activity

transferase activity, transferring phosphorus-containing groups [inference]

phosphotransferase activity, for other substituted phosphate groups

Gene Ontology information from NCBI Gene and UniProt.

Rhea

an N-(2R-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)

a 1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + a 1,2-diacyl-sn-glycerol

Enzyme

2.7.1.227

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP010822
Gene Name: inositol phosphorylceramide synthase 2

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024