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clathrin heavy chain like 1

Summary

Gene Symbol

CLTCL1

Organism

Homo sapiens (human)

External Links

NCBI Gene

8218

PubChem

8218

Alliance of Genome Resources

HGNC:2093

Annotation

Keyword

Acetylation
Alternative splicing
Coated pit
Cytoplasmic vesicle
Phosphoprotein
Proteomics identification
Reference proteome
Repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P53675	Clathrin heavy chain on chromosome 22
A0A087WX41

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
mitotic cell cycle	IDA	19509056 20065094
intracellular protein transport	IEA
receptor-mediated endocytosis	IDA	19509056
receptor-mediated endocytosis	IBA
anatomical structure morphogenesis	TAS	8733128

GO Hierarchy

biological process

cellular process [inference]

cell cycle [inference]

mitotic cell cycle

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

endosomal transport [inference]

retrograde transport, endosome to Golgi

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

cytosolic transport [inference]

retrograde transport, endosome to Golgi

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

developmental process [inference]

anatomical structure morphogenesis

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

endosomal transport [inference]

retrograde transport, endosome to Golgi

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

cytosolic transport [inference]

retrograde transport, endosome to Golgi

organic substance transport [inference]

protein transport [inference]

intracellular protein transport

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

cytosolic transport [inference]

retrograde transport, endosome to Golgi

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

cytosolic transport [inference]

retrograde transport, endosome to Golgi

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of glucose transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

regulation of glucose import [inference]

positive regulation of glucose import

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

regulation of glucose transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

regulation of glucose import [inference]

positive regulation of glucose import

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
early endosome	IDA	20065094
late endosome	IDA	20065094
trans-Golgi network	IDA	19509056
spindle	IDA	19509056
cytosol	TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

membrane coat [inference]

clathrin coat [inference]

clathrin vesicle coat [inference]

clathrin coat of trans-Golgi network vesicle

vesicle coat [inference]

clathrin vesicle coat [inference]

clathrin coat of trans-Golgi network vesicle

clathrin complex

cellular anatomical entity [inference]

cytosol

membrane

plasma membrane

plasma membrane region [inference]

clathrin-coated pit

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

coated vesicle

clathrin-coated vesicle

clathrin-coated endocytic vesicle

endocytic vesicle [inference]

clathrin-coated endocytic vesicle

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

coated vesicle

clathrin-coated vesicle

clathrin-coated endocytic vesicle

endocytic vesicle [inference]

clathrin-coated endocytic vesicle

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

spindle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

coated vesicle

clathrin-coated vesicle

clathrin-coated endocytic vesicle

endocytic vesicle [inference]

clathrin-coated endocytic vesicle

intracellular non-membrane-bounded organelle [inference]

spindle

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 3** entries
GO Term	Evidence Code	PMID
structural molecule activity	IEA
protein binding	IPI	19478182 19509056 36217029
clathrin light chain binding	IBA

GO Hierarchy

molecular function

structural molecule activity

binding [inference]

protein binding

clathrin binding [inference]

clathrin light chain binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

CLATHRIN HEAVY CHAIN

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
clathrin light chain binding
receptor-mediated endocytosis
structural molecule activity

Displaying **all 7** entries
InterPro
Armadillo-type fold
Clathrin heavy chain, N-terminal
Clathrin, heavy chain, linker, core motif
Clathrin, heavy chain, propeller repeat
Clathrin, heavy chain/VPS, 7-fold repeat
Clathrin, heavy chain
Tetratricopeptide-like helical domain superfamily