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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
paraoxonase 1
Summary
- Gene Symbol
-
- Pon1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Calcium
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- HDL
- Hydrolase
- Metal-binding
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P55159 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| lactone catabolic process | ||
| response to fatty acid | ||
| response to fluoride |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| spherical high-density lipoprotein particle | ||
| high-density lipoprotein particle | ||
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| metal ion binding | ||
| phospholipid binding | ||
| arylesterase activity | ||
| acyl-L-homoserine-lactone lactonohydrolase activity | ||
| calcium ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- serum paraoxonase/arylesterase 1
- Functional Category
-
- G: Carbohydrate transport and metabolism
- P: Inorganic ion transport and metabolism
- X: Mobilome: prophages, transposons
| Gene Ontology |
|---|
| acyl-L-homoserine-lactone lactonohydrolase activity |
| aryldialkylphosphatase activity |
| arylesterase activity |
| hydrolase activity |
| metal ion binding |
| response to toxic substance |
| InterPro |
|---|
| Arylesterase |
| Paraoxonase1 |
| Six-bladed beta-propeller, TolB-like |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2355 | anemia | |
| DOID:3083 | chronic obstructive pulmonary disease | |
| DOID:3393 | coronary artery disease | |
| DOID:3526 | cerebral infarction | |
| DOID:4195 | hyperglycemia | |
| DOID:4448 | macular degeneration | |
| DOID:4481 | allergic rhinitis | |
| DOID:576 | proteinuria | |
| DOID:5844 | myocardial infarction | |
| DOID:684 | hepatocellular carcinoma |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP012808
- Gene Name
- paraoxonase 1
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 114693449 | 10041_0:0014a3 | |||
| 116098551 | 35658_0:00203c | |||
| 116902979 | 10117_0:002b7e | |||
| 117720547 | 61156_0:0037ec | |||
| 118580047 | 38674_0:001287 | |||
| 119808400 | 1047088_0:000cfc | |||
| 121463389 | 111838_0:00398c | |||
| 122111944 | 105255_0:001dc6 | |||
| 124080461 | 9995_0:003e55 | |||
| 124991773 | 30640_0:002b40 |
