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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
paraoxonase 1
Summary
- Gene Symbol
-
- Pon1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Calcium
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- HDL
- Hydrolase
- Metal-binding
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P55159 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| lactone catabolic process | ||
| response to fatty acid | ||
| response to fluoride |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| spherical high-density lipoprotein particle | ||
| high-density lipoprotein particle | ||
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| metal ion binding | ||
| phospholipid binding | ||
| arylesterase activity | ||
| acyl-L-homoserine-lactone lactonohydrolase activity | ||
| calcium ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- serum paraoxonase/arylesterase 1
- Functional Category
-
- G: Carbohydrate transport and metabolism
- P: Inorganic ion transport and metabolism
- X: Mobilome: prophages, transposons
| Gene Ontology |
|---|
| acyl-L-homoserine-lactone lactonohydrolase activity |
| aryldialkylphosphatase activity |
| arylesterase activity |
| hydrolase activity |
| metal ion binding |
| response to toxic substance |
| InterPro |
|---|
| Arylesterase |
| Paraoxonase1 |
| Six-bladed beta-propeller, TolB-like |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:7693 | abdominal aortic aneurysm | |
| DOID:83 | cataract | |
| DOID:8577 | ulcerative colitis | |
| DOID:8778 | Crohn's disease | |
| DOID:8947 | diabetic retinopathy | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9538 | multiple myeloma | |
| DOID:9744 | type 1 diabetes mellitus | |
| DOID:9952 | acute lymphoblastic leukemia |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP012808
- Gene Name
- paraoxonase 1
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 104847857 | 885580_0:00054c | |||
| 106000583 | 10020_0:004795 | |||
| 107144451 | 9994_0:003539 | |||
| 109693468 | 51338_0:002d7b | |||
| 110296505 | 10089_0:0018a7 | |||
| 110316677 | 10093_0:000bdf | |||
| 110559638 | 10047_0:003401 | |||
| 113184743 | 9999_0:0016c4 | |||
| 114107955 | 93162_0:003f6e | |||
| 114630828 | 491861_0:002820 |
