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magnesium transporter 1

Summary

Gene Symbol

MAGT1

Organism

Homo sapiens (human)

External Links

NCBI Gene

84061

PubChem

84061

Alliance of Genome Resources

HGNC:28880

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Congenital disorder of glycosylation
Disease variant
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Magnesium
Proteomics identification
Reference proteome
Signal
Transmembrane helix
Transport

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A087WU53	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1
Q9H0U3	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1 Implantation-associated protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protein N-linked glycosylation	NAS	18455129
protein N-linked glycosylation	IMP	31036665
magnesium ion transport	IMP	19717468
protein N-linked glycosylation via asparagine	IMP	25135935
protein N-linked glycosylation via asparagine	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

cellular process [inference]

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

magnesium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

magnesium ion transmembrane transport

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

magnesium ion transport

magnesium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

magnesium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

magnesium ion transmembrane transport

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

magnesium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

magnesium ion transmembrane transport

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum	IDA	25135935
endoplasmic reticulum membrane	NAS	31831667
plasma membrane	NAS	19717468
plasma membrane	TAS
oligosaccharyltransferase complex	IDA	15835887 25135935

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

oligosaccharyltransferase complex

endoplasmic reticulum protein-containing complex [inference]

oligosaccharyltransferase complex

catalytic complex [inference]

transferase complex [inference]

oligosaccharyltransferase complex

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane [inference]

azurophil granule membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane [inference]

azurophil granule membrane

secretory granule membrane [inference]

azurophil granule membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying 1 entry
GO Term	Evidence Code	PMID
magnesium ion transmembrane transporter activity	TAS

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

magnesium ion transmembrane transporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

magnesium ion transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying 1 entry
Gene Ontology
protein N-linked glycosylation via asparagine

Displaying **all 2** entries
InterPro
Oligosaccharyl transferase complex, subunit OST3/OST6
Thioredoxin-like superfamily

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0080319	X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia	Alliance of Genome Resources
DOID:0111839	congenital disorder of glycosylation Icc	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 68 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	7991	SGD:S000005611
Xenopus tropicalis	34137	Xenbase:XB-GENE-998606
Mus musculus	67075	Xenbase:XB-GENE-998606	MOUSE64704
Saccharomyces cerevisiae S288C	80286	SGD:S000005611
Xenopus tropicalis	84061	Xenbase:XB-GENE-998606
Rattus norvegicus	116967	Xenbase:XB-GENE-998606	RATNO44912
Danio rerio	324944	Xenbase:XB-GENE-998606	DANRE06800
Pan troglodytes	465726		PANTR46345
Canis lupus familiaris	491975		CANLF19912
Xenopus tropicalis	494750	Xenbase:XB-GENE-998606

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OrthoDB (Group)

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Acknowledgements