GlyCosmos Portal

Submissions

RNA polymerase I subunit B

Summary

Gene Symbol

POLR1B

Organism

Homo sapiens (human)

External Links

NCBI Gene

84172

PubChem

84172

Alliance of Genome Resources

HGNC:20454

JoGo

POLR1B

TogoVar

POLR1B

Annotation

Keyword

3D-structure
Alternative splicing
Chromosome
DNA-directed RNA polymerase
Disease variant
Magnesium
Nucleotidyltransferase
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Zinc-finger

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B7Z1W6
Q9H9Y6	DNA-directed RNA polymerase I 135 kDa polypeptide

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
transcription by RNA polymerase IV	IEA
transcription by RNA polymerase V	IEA
transcription by RNA polymerase I	IEA
transcription by RNA polymerase II	IEA
transcription by RNA polymerase III	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial transcription

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular developmental process [inference]

cell differentiation [inference]

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition [inference]

neural crest formation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

nucleus organization [inference]

nucleolus organization [inference]

nucleologenesis

cellular component biogenesis [inference]

nucleologenesis

reproductive process [inference]

embryo implantation

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

neural crest formation

cellular developmental process [inference]

cell differentiation [inference]

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition [inference]

neural crest formation

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
fibrillar center	IDA
nucleoplasm	TAS
chromosome	ISS
RNA polymerase I complex	IDA	34671025 36271492
RNA polymerase I complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

nuclear DNA-directed RNA polymerase complex [inference]

RNA polymerase I complex

intracellular protein-containing complex [inference]

RNA polymerase complex [inference]

DNA-directed RNA polymerase complex [inference]

nuclear DNA-directed RNA polymerase complex [inference]

RNA polymerase I complex

catalytic complex [inference]

transferase complex [inference]

transferase complex, transferring phosphorus-containing groups [inference]

RNA polymerase complex [inference]

DNA-directed RNA polymerase complex [inference]

nuclear DNA-directed RNA polymerase complex [inference]

RNA polymerase I complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

chromosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular non-membrane-bounded organelle [inference]

chromosome

Displaying entries **1 - 5** of 8 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
DNA binding	IEA
DNA-directed 5'-3' RNA polymerase activity	IDA	34671025 36271492
DNA-directed 5'-3' RNA polymerase activity	IBA
DNA-directed 5'-3' RNA polymerase activity	IEA
protein binding	IPI	16514417 19214185 20208542 26496610 35271311

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity [inference]

RNA polymerase activity [inference]

5'-3' RNA polymerase activity [inference]

DNA-directed 5'-3' RNA polymerase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

RNA polymerase activity [inference]

5'-3' RNA polymerase activity [inference]

DNA-directed 5'-3' RNA polymerase activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleoside binding [inference]

ribonucleoside binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

organic cyclic compound binding [inference]

nucleoside binding [inference]

ribonucleoside binding

nucleic acid binding [inference]

carbohydrate derivative binding [inference]

nucleoside binding [inference]

ribonucleoside binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

dna-directed rna polymerase i

Functional Category

H: Coenzyme transport and metabolism
J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
metal ion binding
nucleotidyltransferase activity
ribonucleoside binding
transferase activity

Displaying entries **1 - 10** of 12 in total

1

2

Next ›

Last »
InterPro
DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily
DNA-directed RNA polymerase, subunit 2, hybrid-binding domain
DNA-directed RNA polymerase, subunit 2
RNA polymerase Rpb2, OB-fold
RNA polymerase Rpb2, domain 2 superfamily
RNA polymerase Rpb2, domain 2
RNA polymerase Rpb2, domain 3
RNA polymerase Rpb2, domain 4
RNA polymerase Rpb2, domain 5
RNA polymerase Rpb2, domain 7

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0080792	Treacher Collins syndrome 4	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements