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junctophilin 4

Summary

Gene Symbol

JPH4

Organism

Homo sapiens (human)

External Links

NCBI Gene

84502

PubChem

84502

Alliance of Genome Resources

HGNC:20156

Annotation

Keyword

Cell membrane
Endoplasmic reticulum
Reference proteome
Repeat
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q96JJ6	Junctophilin-like 1 protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
regulation of cytokine production	IEA
learning	IEA
regulation of synaptic plasticity	IBA
neuromuscular process controlling balance	IEA
regulation of ryanodine-sensitive calcium-release channel activity	TAS	19095005

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

calcium ion transport into cytosol

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

calcium ion transport into cytosol

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning

neuromuscular process [inference]

neuromuscular process controlling balance

behavior [inference]

learning or memory [inference]

learning

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

calcium ion transport into cytosol

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

calcium ion transport into cytosol

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

calcium ion transport into cytosol

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

calcium ion transport into cytosol

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

calcium ion transport into cytosol

organic substance transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

calcium ion transport into cytosol

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

regulation of calcium ion transmembrane transporter activity [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of cation channel activity [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of calcium ion transmembrane transporter activity [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of cation channel activity [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of calcium ion transmembrane transporter activity [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of store-operated calcium entry

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of calcium ion transmembrane transporter activity [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of cation channel activity [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of sequestering of calcium ion [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

regulation of calcium ion transmembrane transporter activity [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of cation channel activity [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of calcium ion transmembrane transporter activity [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of cation channel activity [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of sequestering of calcium ion [inference]

regulation of release of sequestered calcium ion into cytosol [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of multicellular organismal process [inference]

regulation of cytokine production

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration [inference]

calcium ion transport into cytosol

regulation of synaptic plasticity

regulation of molecular function [inference]

regulation of transporter activity [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

regulation of calcium ion transmembrane transporter activity [inference]

regulation of ryanodine-sensitive calcium-release channel activity

regulation of cation channel activity [inference]

regulation of ryanodine-sensitive calcium-release channel activity

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IBA
smooth endoplasmic reticulum	IEA
plasma membrane	IBA
junctional sarcoplasmic reticulum membrane	TAS	19095005
junctional membrane complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

junctional membrane complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

sarcoplasmic reticulum membrane [inference]

junctional sarcoplasmic reticulum membrane

bounding membrane of organelle [inference]

sarcoplasmic reticulum membrane [inference]

junctional sarcoplasmic reticulum membrane

dendritic shaft

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum [inference]

smooth endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum [inference]

smooth endoplasmic reticulum

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	32296183

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Junctophilin

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Junctophilin
MORN repeat

Ortholog

Displaying entries **11 - 20** of 49 in total

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Species	Gene ID	Orthologous MAtrix
Sus scrofa	100152448	PIGXX32280
Callithrix jacchus	100401534	CALJA00624
Pongo abelii	100442549	PONAB08324
Anolis carolinensis	100553680	ANOCA11244
Nomascus leucogenys	100603279	NOMLE21066
Cavia porcellus	100723843	CAVPO07709
Otolemur garnettii	100966007	OTOGA01715
Papio anubis	101007217	PAPAN36434
Saimiri boliviensis boliviensis	101054465	SAIBB07385
Felis catus	101096486	FELCA12694