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Standards Ontologies Notations
ST6 beta-galactoside alpha-2,6-sialyltransferase 2

Summary
Gene Symbol
  • ST6GAL2
Aliases
  • KIAA1877
  • St6GalII
Organism
Homo sapiens (human)
External Links
NCBI Gene
84620
GGDB ID
HGNC
10861
mRNA
map
  • 2q11.2-q12.1
Protein
OMIM
KEGG Gene ID
hsa:84620
PubChem
84620
Alliance of Genome Resources
Annotation
Keyword
  • Alternative splicing
  • Disulfide bond
  • Glycoprotein
  • Glycosyltransferase
  • Golgi apparatus
  • Reference proteome
  • Signal-anchor
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
Q96JF0
  • CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2
  • ST6Gal II
  • Sialyltransferase 2
Annotation information from UniProt.
Gene Ontology (GO)
Gene Ontology information from NCBI Gene and UniProt.
GlycoGene Database (GGDB)
GGDB ID
gg055
Gene Symbol
  • ST6GAL2
Reactions
Displaying all 3 entries
Donor Acceptor Product Reference
CMP-Neu5Ac
G00055MO
CMP-Neu5Ac
G00057MO
G54118CT
CMP-Neu5Ac
G58896AZ
G83513YI
Displaying all 4 entries
Donor Acceptor Product Reference
CMP-Neu5Ac
G00055MO
CMP-Neu5Ac
G58896AZ
G83513YI
CMP-Neu5Ac
G00057MO
G54118CT
CMP-Neu5Ac
G58896AZ
Displaying all 6 entries
Donor Acceptor Product Reference
CMP-Neu5Ac
G00056MO
CMP-Neu5Ac
G57321FI
CMP-Neu5Ac
G00049MO
CMP-Neu5Ac
G00031MO
CMP-Neu5Ac
G49108TO
CMP-Neu5Ac
G65889KE
Orthologous Gene
Displaying all 3 entries
Species Protein mRNA
Rattus norvegicus XP_236826 XM_236826
Drosophila melanogaster NP_726474 NM_166684
Mus musculus NP_766417 NM_172829
KEGG BRITE Database
Orthology
K00779
Name
beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2) [EC:2.4.3.1]
References
Reactions
Displaying 1 entry
KEGG Reaction Enzyme Acceptor Product
R06188
Rhea

RHEA:21552

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + CMP-N-acetyl-β-neuraminate
H+ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + CMP
Enzyme
PMID

RHEA:11836

N-acetyl-β-lactosamine + CMP-N-acetyl-β-neuraminate
H+ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosamine + CMP
Enzyme
PMID

RHEA:52104

a β-D-galactoside + CMP-N-acetyl-β-neuraminate
an N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl derivative + H+ + CMP
Enzyme
PMID
Disease
Disease Ontology
Displaying all 4 entries
DO ID Disease Name Source
DOID:1107 esophageal carcinoma
DOID:1612 breast cancer
DOID:3962 thyroid gland follicular carcinoma
DOID:5041 esophageal cancer
Ortholog
Displaying entries 1 - 10 of 71 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
37950 FB:FBgn0035050
103172241 CALMI05394
102359235 LATCH12158
403116 ZFIN:ZDB-GENE-060322-4
797439 ZFIN:ZDB-GENE-120426-2
108708393 Xenbase:XB-GENE-17340584
108709694 Xenbase:XB-GENE-17340585
407846 Xenbase:XB-GENE-990439
101950728 CHRPI32195
109306264 CROPO03424
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024