GlyCosmos Portal

Displaying **all 4** entries
GO Term	Evidence Code	PMID
beta-galactoside alpha-2,6-sialyltransferase activity	TAS
beta-galactoside alpha-2,6-sialyltransferase activity	IDA	12235148
beta-galactoside alpha-2,6-sialyltransferase activity	IBA
protein binding	IPI	32296183

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

sialyltransferase activity [inference]

beta-galactoside alpha-2,6-sialyltransferase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Sialyltransferase

Functional Category

H: Coenzyme transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
sialyltransferase activity
transferase activity

Displaying **all 2** entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29

GlycoGene Database (GGDB)

GGDB ID

gg055

Gene Symbol

ST6GAL2

Reactions

Displaying **all 2** entries
Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
CMP-Neu5Ac	G00057MO	Free	G54118CT	Free	12235148
CMP-Neu5Ac	G58896AZ	Free	G83513YI	Free	12235148

Displaying **all 2** entries
Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
CMP-Neu5Ac	G00057MO	Free	G54118CT	Free	12235148
CMP-Neu5Ac	G58896AZ	Free	G83513YI	Free	12235148

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Donor	Acceptor	Reducing terminal(Acceptor)	Reference
CMP-Neu5Ac	G57321FI	para-nitrophenol	12603328
CMP-Neu5Ac	G00049MO	free	12603328
CMP-Neu5Ac	G65889KE	para-nitrophenol	12603328
CMP-Neu5Ac	G00056MO	-O-octyl	12603328
CMP-Neu5Ac	G00031MO	benzyl	12603328

Orthologous Gene

Displaying **all 3** entries
Species	Protein	mRNA
Rattus norvegicus	XP_236826	XM_236826
Mus musculus	NP_766417	NM_172829
Drosophila melanogaster	NP_726474	NM_166684

KEGG BRITE Database

Orthology

K00779

Name

beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2) [EC:2.4.3.1]

References

12235148

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R06188	2.4.3.1	G51331BY	G09376MR

Rhea

RHEA:11836

N-acetyl-β-lactosamine + CMP-N-acetyl-β-neuraminate

H⁺ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosamine + CMP

Enzyme

2.4.3.1

PMID

RHEA:52104

a β-D-galactoside + CMP-N-acetyl-β-neuraminate

an N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl derivative + H⁺ + CMP

Enzyme

2.4.3.1

PMID

RHEA:21552

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + CMP-N-acetyl-β-neuraminate

H⁺ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + CMP

Enzyme

2.4.3.1

PMID

2460092

Ortholog

Displaying entries **1 - 10** of 79 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	523	Xenbase:XB-GENE-990439
Drosophila melanogaster	6480	FB:FBgn0035050
Xenopus tropicalis	11964	Xenbase:XB-GENE-990439
Drosophila melanogaster	20440	FB:FBgn0035050
Drosophila melanogaster	25197	FB:FBgn0035050
Xenopus tropicalis	37950	Xenbase:XB-GENE-990439
Xenopus tropicalis	84620	Xenbase:XB-GENE-990439
Mus musculus	240119	Xenbase:XB-GENE-990439	MOUSE20017
Rattus norvegicus	301155	Xenbase:XB-GENE-990439	RATNO43159
Xenopus tropicalis	403116	Xenbase:XB-GENE-990439

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

GlycoGene Database (GGDB)

KEGG BRITE Database

International Collaboration

Acknowledgements