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adhesion G protein-coupled receptor E3

Summary

Gene Symbol

ADGRE3

Organism

Homo sapiens (human)

External Links

NCBI Gene

84658

PubChem

84658

Alliance of Genome Resources

HGNC:23647

Annotation

Keyword

Alternative splicing
Calcium
Cell membrane
Disulfide bond
EGF-like domain
G-protein coupled receptor
Glycoprotein
Proteomics identification
Receptor
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Proteins

Displaying **all 5** entries
UniProt	Protein Name
Q0IJ53
E7EW83
Q9BY15	EGF-like module receptor 3 EGF-like module-containing mucin-like hormone receptor-like 3
A1L1B9
B7Z5A1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cell surface receptor signaling pathway	IEA
G protein-coupled receptor signaling pathway	TAS	15203201
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

Displaying **all 5** entries
GO Term	Evidence Code	PMID
ficolin-1-rich granule membrane	TAS
secretory granule membrane	TAS
membrane	TAS	15203201
plasma membrane	IBA TAS
extracellular region	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane

ficolin-1-rich granule membrane

bounding membrane of organelle [inference]

secretory granule membrane

ficolin-1-rich granule membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
calcium ion binding	IEA
G protein-coupled receptor activity	IBA

GO Hierarchy

molecular function

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

adhesion g protein-coupled receptor l2

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
cell surface receptor signaling pathway

Displaying 1 entry
InterPro
GPCR, family 2, secretin-like

Ortholog

Displaying entries **1 - 10** of 25 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	448252		Xenbase:XB-GENE-950605
Canis lupus familiaris	484900			CANLF07755
Pan troglodytes	748143	9598_0:004d47		PANTR17426
Pongo abelii	100172916	9601_0:0048c0		PONAB14466
Sus scrofa	100516246			PIGXX18212
Nomascus leucogenys	100585997			NOMLE02264
Loxodonta africana	100674343			LOXAF11682
Otolemur garnettii	100948653			OTOGA05058
Pan paniscus	100975262	9597_0:004caa
Saimiri boliviensis boliviensis	101033030			SAIBB35326