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protein phosphatase 1 regulatory subunit 9B

Summary

Gene Symbol

PPP1R9B

Organism

Homo sapiens (human)

External Links

NCBI Gene

84687

PubChem

84687

Alliance of Genome Resources

HGNC:9298

Annotation

Keyword

Actin-binding
Cell junction
Cell membrane
Cell projection
Coiled coil
Cytoskeleton
Developmental protein
Differentiation
Neurogenesis
Nucleus
Phosphoprotein
Reference proteome
Synapse

Proteins

Displaying 1 entry
UniProt	Protein Name
Q96SB3	Neurabin-II Protein phosphatase 1 regulatory subunit 9B Spinophilin

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 38 in total

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GO Term	Evidence Code	PMID
filopodium assembly	IMP	19151759
neuron projection development	IBA
reproductive system development	IEA
protein localization to cell periphery	IEA
response to immobilization stress	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA splicing

cell motility [inference]

cell migration

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cytoskeleton [inference]

protein localization to actin cytoskeleton

protein localization to cell periphery

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to estradiol stimulus

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to peptide

cellular response to xenobiotic stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to peptide

cellular response to oxygen-containing compound [inference]

cellular response to salt [inference]

cellular response to morphine

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component disassembly [inference]

protein-containing complex disassembly [inference]

protein depolymerization [inference]

actin filament depolymerization

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

filopodium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

filopodium assembly

plasma membrane bounded cell projection organization [inference]

neuron projection development

dendrite development

plasma membrane bounded cell projection assembly [inference]

filopodium assembly

protein-containing complex organization [inference]

protein-containing complex disassembly [inference]

protein depolymerization [inference]

actin filament depolymerization

supramolecular fiber organization [inference]

actin filament organization

actin polymerization or depolymerization [inference]

actin filament depolymerization

reproductive process [inference]

developmental process involved in reproduction

reproductive behavior [inference]

mating behavior [inference]

male mating behavior

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning

behavior [inference]

learning or memory [inference]

learning

reproductive behavior [inference]

mating behavior [inference]

male mating behavior

developmental process [inference]

developmental process involved in reproduction

anatomical structure development [inference]

system development [inference]

reproductive system development

response to stimulus [inference]

response to stress [inference]

response to immobilization stress

response to endogenous stimulus [inference]

response to hormone [inference]

response to prostaglandin [inference]

response to prostaglandin E

response to steroid hormone

response to growth factor [inference]

response to epidermal growth factor [inference]

cellular response to epidermal growth factor stimulus

cellular response to growth factor stimulus [inference]

cellular response to epidermal growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus [inference]

cellular response to epidermal growth factor stimulus

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to peptide

response to chemical [inference]

response to acid chemical [inference]

response to amino acid [inference]

response to kainic acid

response to xenobiotic stimulus [inference]

cellular response to xenobiotic stimulus

response to organic substance [inference]

response to hormone [inference]

response to prostaglandin [inference]

response to prostaglandin E

response to steroid hormone

response to organonitrogen compound [inference]

response to amine [inference]

response to amphetamine

response to amino acid [inference]

response to kainic acid

response to alkaloid [inference]

response to isoquinoline alkaloid [inference]

response to morphine [inference]

cellular response to morphine

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to alkaloid [inference]

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to peptide

response to peptide [inference]

cellular response to peptide

response to L-phenylalanine derivative

response to organic cyclic compound [inference]

response to isoquinoline alkaloid [inference]

response to morphine [inference]

cellular response to morphine

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

response to estradiol [inference]

cellular response to estradiol stimulus

response to steroid hormone

cellular response to organic cyclic compound [inference]

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to estradiol stimulus

response to kainic acid

response to lipid [inference]

response to estradiol [inference]

cellular response to estradiol stimulus

response to prostaglandin [inference]

response to prostaglandin E

response to steroid hormone

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to estradiol stimulus

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to peptide

response to alcohol [inference]

response to prostaglandin E

response to ketone [inference]

response to prostaglandin E

response to nicotine

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to estradiol stimulus

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to peptide

cellular response to xenobiotic stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to peptide

cellular response to oxygen-containing compound [inference]

cellular response to salt [inference]

cellular response to morphine

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to amine [inference]

response to amphetamine

response to amino acid [inference]

response to kainic acid

response to alkaloid [inference]

response to isoquinoline alkaloid [inference]

response to morphine [inference]

cellular response to morphine

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to alkaloid [inference]

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to peptide

response to peptide [inference]

cellular response to peptide

response to L-phenylalanine derivative

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to peptide

response to oxygen-containing compound [inference]

response to estradiol [inference]

cellular response to estradiol stimulus

response to amino acid [inference]

response to kainic acid

response to alcohol [inference]

response to prostaglandin E

response to peptide [inference]

cellular response to peptide

response to ketone [inference]

response to prostaglandin E

cellular response to oxygen-containing compound [inference]

response to salt [inference]

response to morphine [inference]

cellular response to morphine

cellular response to salt [inference]

cellular response to morphine

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to estradiol stimulus

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to peptide

cellular response to xenobiotic stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to alkaloid [inference]

cellular response to isoquinoline alkaloid [inference]

cellular response to morphine

cellular response to peptide

cellular response to oxygen-containing compound [inference]

cellular response to salt [inference]

cellular response to morphine

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cytoskeleton [inference]

protein localization to actin cytoskeleton

protein localization to cell periphery

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cytoskeleton [inference]

protein localization to actin cytoskeleton

protein localization to cell periphery

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of cellular metabolic process [inference]

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation

regulation of nitrogen compound metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation

regulation of macromolecule metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

regulation of opioid receptor signaling pathway

regulation of localization [inference]

regulation of cellular localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell cortex [inference]

positive regulation of protein localization to actin cortical patch

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell cortex [inference]

positive regulation of protein localization to actin cortical patch

regulation of protein localization to cell cortex [inference]

regulation of protein localization to actin cortical patch [inference]

positive regulation of protein localization to actin cortical patch

positive regulation of protein localization to cell cortex [inference]

positive regulation of protein localization to actin cortical patch

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of growth [inference]

regulation of cell growth [inference]

negative regulation of growth [inference]

negative regulation of cell growth

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell cortex [inference]

positive regulation of protein localization to actin cortical patch

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

negative regulation of biological process [inference]

negative regulation of growth [inference]

negative regulation of cell growth

negative regulation of cellular process [inference]

negative regulation of cell growth

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

regulation of opioid receptor signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

regulation of opioid receptor signaling pathway

regulation of cellular metabolic process [inference]

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation

regulation of cell population proliferation

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of postsynapse assembly

positive regulation of cellular process [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell cortex [inference]

positive regulation of protein localization to actin cortical patch

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

negative regulation of cellular process [inference]

negative regulation of cell growth

regulation of cellular component organization [inference]

regulation of cell growth [inference]

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

regulation of postsynapse assembly

regulation of postsynapse organization [inference]

regulation of postsynapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of postsynapse assembly

regulation of cell cycle

regulation of mitotic cell cycle [inference]

regulation of mitotic cell cycle phase transition [inference]

regulation of exit from mitosis

regulation of cell cycle process [inference]

regulation of cell cycle phase transition [inference]

regulation of mitotic cell cycle phase transition [inference]

regulation of exit from mitosis

regulation of cellular localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell cortex [inference]

positive regulation of protein localization to actin cortical patch

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell cortex [inference]

positive regulation of protein localization to actin cortical patch

regulation of protein localization to cell cortex [inference]

regulation of protein localization to actin cortical patch [inference]

positive regulation of protein localization to actin cortical patch

positive regulation of protein localization to cell cortex [inference]

positive regulation of protein localization to actin cortical patch

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
filopodium	IDA	19151759
cortical actin cytoskeleton	IEA
adherens junction	IEA
lamellipodium	IDA	19151759
glutamatergic synapse	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

phosphatase complex [inference]

protein serine/threonine phosphatase complex [inference]

protein phosphatase type 1 complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

cell projection membrane [inference]

ruffle membrane

extrinsic component of membrane [inference]

extrinsic component of plasma membrane [inference]

extrinsic component of synaptic membrane [inference]

extrinsic component of postsynaptic membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

anchoring junction [inference]

cell-cell junction [inference]

adherens junction

site of polarized growth [inference]

growth cone

leading edge membrane [inference]

ruffle membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

lamellipodium

neuron projection [inference]

dendrite

actin-based cell projection [inference]

filopodium

organelle [inference]

membrane-bounded organelle [inference]

spine apparatus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

cortical cytoskeleton [inference]

cortical actin cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

cortical cytoskeleton [inference]

cortical actin cytoskeleton

postsynaptic specialization [inference]

postsynaptic density

cell body [inference]

neuronal cell body

side of membrane [inference]

cytoplasmic side of membrane [inference]

cytoplasmic side of plasma membrane [inference]

cytoplasmic side of dendritic spine plasma membrane

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GO Term	Evidence Code	PMID
protein phosphatase 1 binding	NAS	11278317
transmembrane transporter binding	IEA
D2 dopamine receptor binding	IEA
protein binding	IPI	11278317 15231748 19151759 22321011 24114805 24366813 25593058 25785436 26496610 28330616 28514442 33961781 34591612
kinase binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

binding [inference]

protein binding

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

dopamine receptor binding [inference]

D2 dopamine receptor binding

cytoskeletal protein binding [inference]

actin binding [inference]

actin filament binding

enzyme binding [inference]

kinase binding

phosphatase binding [inference]

protein phosphatase binding [inference]

protein phosphatase 1 binding

transmembrane transporter binding

protein-containing complex binding [inference]

actin filament binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

phosphatase inhibitor activity [inference]

protein phosphatase inhibitor activity

phosphatase regulator activity [inference]

phosphatase inhibitor activity [inference]

protein phosphatase inhibitor activity

protein phosphatase regulator activity [inference]

protein phosphatase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

phosphatase inhibitor activity [inference]

protein phosphatase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:14330	Parkinson's disease	Alliance of Genome Resources
DOID:5419	schizophrenia	Alliance of Genome Resources
DOID:684	hepatocellular carcinoma	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

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Acknowledgements