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solute carrier family 7 member 3

Summary

Gene Symbol

SLC7A3

Organism

Homo sapiens (human)

External Links

NCBI Gene

84889

PubChem

84889

Alliance of Genome Resources

HGNC:11061

Annotation

Keyword

Amino-acid transport
Cell membrane
Glycoprotein
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8WY07	Cationic amino acid transporter y+ Solute carrier family 7 member 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
amino acid transport	TAS
amino acid transport	IBA
L-arginine import across plasma membrane	IDA	11591158
L-lysine import across plasma membrane	IDA	11591158
L-ornithine import across plasma membrane	IDA	11591158

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier

localization [inference]

establishment of localization [inference]

transport [inference]

vascular transport [inference]

transport across blood-brain barrier

transmembrane transport [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

amino acid transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

basic amino acid transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport [inference]

L-lysine transport [inference]

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

ornithine transport [inference]

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

amino acid transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

basic amino acid transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport [inference]

L-lysine transport [inference]

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

ornithine transport [inference]

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

modified amino acid transport [inference]

nitrogen compound transport [inference]

amino acid transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

basic amino acid transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport [inference]

L-lysine transport [inference]

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

ornithine transport [inference]

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

modified amino acid transport [inference]

import into cell [inference]

amino acid import across plasma membrane [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IDA	11591158 16332251
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
L-ornithine transmembrane transporter activity	IDA	11591158
protein binding	IPI	32296183
amino acid transmembrane transporter activity	TAS
amino acid transmembrane transporter activity	IBA
L-lysine transmembrane transporter activity	IDA	11591158

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity

basic amino acid transmembrane transporter activity [inference]

L-amino acid transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity

basic amino acid transmembrane transporter activity [inference]

L-amino acid transmembrane transporter activity [inference]

modified amino acid transmembrane transporter activity [inference]

L-arginine transmembrane transporter activity

salt transmembrane transporter activity [inference]

L-lysine transmembrane transporter activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

permease

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying 1 entry
InterPro
Amino acid permease/ SLC12A domain

Ortholog

Displaying entries **1 - 10** of **102** in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	6541	SGD:S000006195
Saccharomyces cerevisiae S288C	6542	SGD:S000006195
Saccharomyces cerevisiae S288C	6545	SGD:S000006195
Drosophila melanogaster	11987	FB:FBgn0037203
Saccharomyces cerevisiae S288C	11988	SGD:S000001839
Mus musculus	11989	Xenbase:XB-GENE-1002485	MOUSE66615
Rattus norvegicus	29485	Xenbase:XB-GENE-1002485	RATNO44562
Saccharomyces cerevisiae S288C	57709	SGD:S000006195
Saccharomyces cerevisiae S288C	64554	SGD:S000001839
Xenopus tropicalis	84889	Xenbase:XB-GENE-1002485