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immunoglobin superfamily member 21

Summary

Gene Symbol

IGSF21

Organism

Homo sapiens (human)

External Links

NCBI Gene

84966

PubChem

84966

Alliance of Genome Resources

HGNC:28246

Annotation

Keyword

Cell membrane
Disulfide bond
GPI-anchor
Immunoglobulin domain
Postsynaptic cell membrane
Proteomics identification
Reference proteome
Repeat
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q96ID5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IBA
trans-synaptic signaling, modulating synaptic transmission	IEA
homophilic cell adhesion via plasma membrane adhesion molecules	IBA
synapse maturation	ISS

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

trans-synaptic signaling, modulating synaptic transmission

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell junction organization [inference]

synapse organization [inference]

synapse maturation

developmental process [inference]

developmental maturation [inference]

synapse maturation

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

trans-synaptic signaling, modulating synaptic transmission

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

trans-synaptic signaling, modulating synaptic transmission

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

trans-synaptic signaling, modulating synaptic transmission

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GO Term	Evidence Code	PMID
external side of plasma membrane	ISS
inhibitory synapse	ISS
postsynaptic membrane
postsynaptic density membrane	IEA
adherens junction	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

synapse [inference]

inhibitory synapse

anchoring junction [inference]

cell-cell junction [inference]

adherens junction

side of membrane [inference]

external side of plasma membrane

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Immunoglobulin

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 3** entries
InterPro
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold

Ortholog

Displaying entries **1 - 10** of 53 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	230868		MGI:2681842	MOUSE41728
Rattus norvegicus	298591		RGD:1310117	RATNO33461
Xenopus laevis	444673		Xenbase:XB-GENE-5948994
Pan troglodytes	456572	9598_0:00012c		PANTR20086
Canis lupus familiaris	478214			CANLF07103
Bos taurus	508119			BOVIN25357
Danio rerio	567714		ZFIN:ZDB-GENE-070424-59
Danio rerio	569872		ZFIN:ZDB-GENE-050809-118	DANRE02020
Macaca mulatta	701539			MACMU22821
Xenopus tropicalis	779688		Xenbase:XB-GENE-5948979