GlyCosmos Portal

GlyTouCan

Glycan Structure Repository

GlyComb

Glycoconjugate Repository

GlycoPOST

Glycomics MS raw data Repository

UniCarb-DR

Glycomics MS Repository for glycan annotations from GlycoWorkbench

All Resources

Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

Other Information

Release Statistics Download

Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

3-isopropylmalate dehydrogenase

Summary

Gene Symbol

LEU2

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

850342

PubChem

850342

Alliance of Genome Resources

SGD:S000000523

Annotation

Keyword

Cytoplasm
Leucine biosynthesis
Magnesium
Manganese
Metal-binding
NAD
Oxidoreductase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P04173	Beta-IPM dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
glyoxylate cycle	IMP	23642236
amino acid biosynthetic process
leucine biosynthetic process	IBA IEA IMP	6297759

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

alpha-amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

alpha-amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

glyoxylate cycle

amino acid metabolic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

alpha-amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

alpha-amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

glyoxylate cycle

cellular aldehyde metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

alpha-amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

alpha-amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

alpha-amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytosol	IBA IDA	4355481
cytoplasm	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 5** entries
GO Term	Evidence Code	PMID
oxidoreductase activity	IEA
3-isopropylmalate dehydrogenase activity	IBA IDA IEA IMP	3071718 6297759
magnesium ion binding	IEA
NAD binding	IEA
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

3-isopropylmalate dehydrogenase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

ion binding [inference]

cation binding [inference]

metal ion binding

magnesium ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
cytosol	PMID:4355481

About Release Notes Help Feedback

Click here to visit the beta site.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

GlyCosmos Portal v4.0.0

Last updated: August 19, 2024