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D-xylulose reductase XYL2

Summary

Gene Symbol

XYL2

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

850759

PubChem

850759

Alliance of Genome Resources

SGD:S000004060

Annotation

Keyword

Metal-binding
NAD
Oxidoreductase
Reference proteome
Xylose metabolism
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
Q07993	Xylitol dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
sorbitol catabolic process	IBA
xylulose biosynthetic process	IDA	10486580
D-xylose metabolic process	IEA
L-arabinose catabolic process to xylulose 5-phosphate	IEA

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

small molecule catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

monosaccharide catabolic process [inference]

pentose catabolic process [inference]

arabinose catabolic process [inference]

L-arabinose catabolic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

monosaccharide catabolic process [inference]

pentose catabolic process [inference]

arabinose catabolic process [inference]

L-arabinose catabolic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

biosynthetic process [inference]

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

pentose biosynthetic process [inference]

xylulose biosynthetic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

pentose biosynthetic process [inference]

xylulose biosynthetic process

organophosphate biosynthetic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

carbohydrate derivative biosynthetic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

xylulose 5-phosphate metabolic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

organophosphate metabolic process [inference]

xylulose 5-phosphate metabolic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

organophosphate biosynthetic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

pentose metabolic process [inference]

xylulose metabolic process [inference]

xylulose biosynthetic process

pentose biosynthetic process [inference]

xylulose biosynthetic process

pentose catabolic process [inference]

arabinose catabolic process [inference]

L-arabinose catabolic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

arabinose metabolic process [inference]

arabinose catabolic process [inference]

L-arabinose catabolic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

L-arabinose metabolic process [inference]

L-arabinose catabolic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

D-xylose metabolic process

monosaccharide biosynthetic process [inference]

pentose biosynthetic process [inference]

xylulose biosynthetic process

monosaccharide catabolic process [inference]

pentose catabolic process [inference]

arabinose catabolic process [inference]

L-arabinose catabolic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

pentose biosynthetic process [inference]

xylulose biosynthetic process

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

monosaccharide catabolic process [inference]

pentose catabolic process [inference]

arabinose catabolic process [inference]

L-arabinose catabolic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol catabolic process

hexitol catabolic process [inference]

sorbitol catabolic process

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

pentose metabolic process [inference]

xylulose metabolic process [inference]

xylulose biosynthetic process

pentose biosynthetic process [inference]

xylulose biosynthetic process

pentose catabolic process [inference]

arabinose catabolic process [inference]

L-arabinose catabolic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

arabinose metabolic process [inference]

arabinose catabolic process [inference]

L-arabinose catabolic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

L-arabinose metabolic process [inference]

L-arabinose catabolic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

D-xylose metabolic process

monosaccharide biosynthetic process [inference]

pentose biosynthetic process [inference]

xylulose biosynthetic process

monosaccharide catabolic process [inference]

pentose catabolic process [inference]

arabinose catabolic process [inference]

L-arabinose catabolic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol catabolic process

hexitol catabolic process [inference]

sorbitol catabolic process

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

small molecule catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

monosaccharide catabolic process [inference]

pentose catabolic process [inference]

arabinose catabolic process [inference]

L-arabinose catabolic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

pentose biosynthetic process [inference]

xylulose biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

pentose metabolic process [inference]

xylulose metabolic process [inference]

xylulose biosynthetic process

pentose biosynthetic process [inference]

xylulose biosynthetic process

pentose catabolic process [inference]

arabinose catabolic process [inference]

L-arabinose catabolic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

arabinose metabolic process [inference]

arabinose catabolic process [inference]

L-arabinose catabolic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

L-arabinose metabolic process [inference]

L-arabinose catabolic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

D-xylose metabolic process

monosaccharide biosynthetic process [inference]

pentose biosynthetic process [inference]

xylulose biosynthetic process

monosaccharide catabolic process [inference]

pentose catabolic process [inference]

arabinose catabolic process [inference]

L-arabinose catabolic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

pentose biosynthetic process [inference]

xylulose biosynthetic process

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

monosaccharide catabolic process [inference]

pentose catabolic process [inference]

arabinose catabolic process [inference]

L-arabinose catabolic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol catabolic process

hexitol catabolic process [inference]

sorbitol catabolic process

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

organophosphate metabolic process [inference]

xylulose 5-phosphate metabolic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

organophosphate biosynthetic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

carbohydrate derivative metabolic process [inference]

xylulose 5-phosphate metabolic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

carbohydrate derivative biosynthetic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

monosaccharide catabolic process [inference]

pentose catabolic process [inference]

arabinose catabolic process [inference]

L-arabinose catabolic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

pentose biosynthetic process [inference]

xylulose biosynthetic process

organophosphate biosynthetic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

carbohydrate derivative biosynthetic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol catabolic process

hexitol catabolic process [inference]

sorbitol catabolic process

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

xylulose 5-phosphate metabolic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

organophosphate metabolic process [inference]

xylulose 5-phosphate metabolic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

organophosphate biosynthetic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

L-arabinose catabolic process to xylulose 5-phosphate

Displaying 1 entry
GO Term	Evidence Code	PMID
cellular_component	ND

GO Hierarchy

cellular component

Displaying entry **6 - 6** of 6 in total

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2
GO Term	Evidence Code	PMID
L-iditol 2-dehydrogenase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

hexitol dehydrogenase activity [inference]

D-xylulose reductase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0081376	obsolete sorbitol dehydrogenase deficiency with peripheral neuropathy	Alliance of Genome Resources
DOID:0081427	autosomal recessive distal hereditary motor neuronopathy 8	Alliance of Genome Resources
DOID:83	cataract	Alliance of Genome Resources
DOID:9743	diabetic neuropathy	Alliance of Genome Resources

Ortholog

Displaying **all 9** entries
Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	179404	WB:WBGene00011004
Caenorhabditis elegans	179405	WB:WBGene00011003
Drosophila melanogaster	40836	FB:FBgn0024289
Drosophila melanogaster	41313	FB:FBgn0022359
Danio rerio	570613	ZFIN:ZDB-GENE-040426-1231
Xenopus tropicalis	496715	Xenbase:XB-GENE-1005865
Homo sapiens	6652	HGNC:11184
Mus musculus	20322	MGI:98266
Rattus norvegicus	24788	RGD:3734

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