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trehalose-phosphatase TPS2

Summary

Gene Symbol

TPS2

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

851646

KEGG Gene ID

sce:YDR074W

PubChem

851646

Alliance of Genome Resources

SGD:S000002481

Annotation

Keyword

Cytoplasm
Direct protein sequencing
Hydrolase
Reference proteome
Stress response

Proteins

Displaying 1 entry
UniProt	Protein Name
P31688	Trehalose synthase complex catalytic subunit TPS2 Trehalose-6-phosphate phosphatase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
cellular response to heat
trehalose biosynthetic process	IBA IEA IMP	8203161 8444170
fungal-type cell wall organization
trehalose metabolism in response to stress	IBA IMP	9837904
positive regulation of autophagy	IMP	32240040

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

trehalose biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

disaccharide metabolic process [inference]

trehalose metabolic process

disaccharide biosynthetic process [inference]

trehalose biosynthetic process

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

trehalose biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

trehalose biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

disaccharide metabolic process [inference]

trehalose metabolic process

disaccharide biosynthetic process [inference]

trehalose biosynthetic process

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

trehalose biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

trehalose biosynthetic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process [inference]

disaccharide biosynthetic process [inference]

trehalose biosynthetic process

cellular process [inference]

cell communication [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to nitrogen starvation

cellular response to nitrogen levels [inference]

cellular response to nitrogen starvation

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to nitrogen starvation

cellular response to nitrogen levels [inference]

cellular response to nitrogen starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to nitrogen starvation

cellular response to heat

cell wall organization or biogenesis [inference]

cell wall organization [inference]

fungal-type cell wall organization

fungal-type cell wall organization or biogenesis [inference]

fungal-type cell wall organization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

external encapsulating structure organization [inference]

cell wall organization [inference]

fungal-type cell wall organization

response to stimulus [inference]

response to stress [inference]

response to heat [inference]

cellular response to heat

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to nitrogen starvation

cellular response to heat

response to starvation [inference]

cellular response to starvation [inference]

cellular response to nitrogen starvation

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to nitrogen starvation

cellular response to nitrogen levels [inference]

cellular response to nitrogen starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to nitrogen starvation

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to nitrogen starvation

cellular response to nitrogen levels [inference]

cellular response to nitrogen starvation

cellular response to external stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to nitrogen starvation

cellular response to nitrogen levels [inference]

cellular response to nitrogen starvation

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat [inference]

cellular response to heat

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to nitrogen starvation

cellular response to nitrogen levels [inference]

cellular response to nitrogen starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to nitrogen starvation

cellular response to heat

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

positive regulation of autophagy

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

positive regulation of autophagy

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

positive regulation of autophagy

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

Displaying **all 3** entries
GO Term	Evidence Code	PMID
mitochondrion	HDA	14576278 16823961
alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)	IBA IPI	9837904
cytoplasm	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

transferase complex [inference]

alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)

cellular anatomical entity [inference]

cytoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 4** entries
GO Term	Evidence Code	PMID
hydrolase activity	IEA
catalytic activity	IEA
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity
trehalose-phosphatase activity	IBA IEA IMP	8444170 9837904

GO Hierarchy

molecular function

catalytic activity

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

UDP-glucosyltransferase activity [inference]

alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity

hexosyltransferase activity [inference]

glucosyltransferase activity [inference]

UDP-glucosyltransferase activity [inference]

alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity

hydrolase activity

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

carbohydrate phosphatase activity [inference]

trehalose-phosphatase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

alpha,alpha-trehalose-phosphate synthase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
H: Coenzyme transport and metabolism

Displaying **all 5** entries
Gene Ontology
catalytic activity
trehalose biosynthetic process
trehalose metabolic process
trehalose metabolism in response to stress
trehalose-phosphatase activity

Displaying **all 4** entries
InterPro
Glycosyl transferase, family 20
HAD superfamily
HAD-like superfamily
Trehalose-phosphatase

KEGG BRITE Database

Orthology

K16055

Name

trehalose 6-phosphate synthase/phosphatase [EC:2.4.1.15 3.1.3.12]

References

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)	PMID:9837904
mitochondrion	PMID:14576278 PMID:16823961

Rhea

RHEA:23420

H₂O + α,α-trehalose 6-phosphate

α,α-trehalose + phosphate

Enzyme

3.1.3.12

PMID

Ortholog

Displaying entries **1 - 10** of 25 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Drosophila melanogaster	33642		FB:FBgn0027560
Kluyveromyces lactis	2894138	28985_0:000b88
Caenorhabditis elegans	3565050		WB:WBGene00006603
Eremothecium gossypii ATCC 10895	4623100	284811_0:000fda
Vanderwaltozyma polyspora DSM 70294	5546728	436907_0:00100e
Zygosaccharomyces rouxii	8206446	4956_0:001215
Lachancea thermotolerans CBS 6340	8294525	559295_0:001291
Eremothecium cymbalariae DBVPG#7215	11468636	931890_0:000aaf
Naumovozyma dairenensis CBS 421	11495310	1071378_0:00023f
Torulaspora delbrueckii	11504623	4950_0:00034b